1 results about "Melanocyte" patented technology

The invention relates to a microneedle for treating leucoderma as well as a preparation method and application thereof, and relates to the field of medical biological materials. The microneedle comprises hydrogel, a water-soluble substrate material and an active pharmaceutical ingredient, the active pharmaceutical ingredient is selected from at least one of the following raw materials: melanotropin, tofacitinib, tacrolimus, pimerolimus or ruxolitinib. According to the microneedle, hydrogel with high mechanical strength is adopted, the microneedle can pierce the cuticle, the hydrogel is insoluble in water, the prepared microneedle does not need a large amount of organic solvent, after the microneedle pierces the cuticle, the medicine for treating leucoderma is directly delivered to the epidermal layer and the corium layer through the diffusion effect, and the medicine application effect is enhanced; meanwhile, the substrate of the microneedle is made of a water-soluble substrate material, after the skin is punctured by the microneedle, water is absorbed, the tip of the microneedle and the substrate of the microneedle are automatically separated, and the tip which is insoluble in water is remained in the skin, so that active pharmaceutical ingredients attached to the microneedle are released in a long-acting manner, and the administration frequency is reduced.