The invention discloses a two-core twisted-pair cable. The two-core twisted-pair cable comprises main cable cores, a tape wrapping layer, a waterproof layer, a shielding layer and a protective jacket. The main cable cores are divided into three sets, and each set of main cable core is formed by two tin plating insulating cable cores in a twisted-pair mode. A reinforcing plate is arranged inside the tape wrapping layer, and the cross section of the reinforcing plate is formed by the way that three insulating plates intersect at one end. The tape wrapping layer is evenly divided into three windowpanes, and the main cable cores are located in the three windowpanes respectively. The shielding layer is formed by the way that an inner shielding layer is in cross linkage with an outer shielding layer. The two-core twisted-pair cable is good in electrical conductivity, long in service life, resistant to high temperatures, fireproof, resistant to oil, capable of protecting corrosion, mainly applicable to the fields of computers, communication, electricity generation, chemical engineering, petroleum and the like, waterproof, resistant to oxidation, high in shielding property, resistant to dragging, and firm in cable core.