Method of establishing crania-cerebral explosion impact injury animal model
A technology of explosive impact and animal models, applied in the field of medical research, to achieve the effect of simple structure of the experimental device and prevention of heat wave burns
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Embodiment 1
[0020] The method for establishing the animal model of craniocerebral blast injury in this example is as follows: Figure 1 and Figure four As shown, the rat 7 is fixed on the shielding plate 2 with the window hole 3, and the back side of the head of the rat 7 is aligned with the window hole 3 of the shielding plate, so that only the back side of the head of the rat 7 can be damaged by the shock wave; The adjustment hole 4 corresponds to the shielding plate window hole 3; the shielding plate 2 is fixed, and the pressure detector 9 and the explosion source 8 are placed on the same horizontal plane as the shielding plate window hole 3, so that the explosion source 8 is far from the shielding plate window hole 3 and the pressure detector 9 The distances are equal; the detonation causes injury, records the shock wave pressure data and the head injury of rats, and establishes an animal model of craniocerebral blast injury.
[0021] In this example, the explosion source is a paper...
Embodiment 2
[0024] The method for establishing the animal model of craniocerebral blast injury in this example is as follows: Figure II , Figure three and Figure four As shown, the shielding plate 2 is one side of the shock wave shielding box 1, and can be opened as the shielding door of the shock wave shielding box 1; there is a window 3 on the shielding door, and rats 7 are fixed on the shielding door, and 7 rats The back side of the head is aligned with the shielding door and window hole 3, so that only the back of the head of the rat 7 can be damaged by the shock wave; the appropriate adjustment hole 4 is selected to correspond to the shielding plate window hole 3; a pressure detector 9 is placed on the same level as the shielding door and window hole 3 and the explosion source 8, so that the distance from the explosion source 8 to the shielding door window hole 3 and the pressure detector 9 is equal; detonation causes injury, records the shock wave pressure data and the head inju...
Embodiment 3
[0028] The method for establishing the animal model of craniocerebral blast injury in this example is the same as that in Example 2 except that the source of the explosion is a shock wave generating device.
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