Method for preparing tetrahydrobenzo[b][1,8]naphthyridine compound
A technology for tetrahydrobenzene and compounds, which is applied in the field of preparation of tetrahydrobenzo[b][1,8]naphthyridine derivatives, can solve the problems of less development, achieve a wide range of substrates, high reaction yields, and synthetic The effect of simple process
Active Publication Date: 2018-05-25
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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Benefits of technology
This patented method simplifies the production processes for certain chemicals by allowing them to be mixed together quickly without having multiple stages or starting materials at once. It also results in products with new structures that are highly effective because they have different types of molecules attached on their surface.
Problems solved by technology
The technical problem addressed by this patented article relates to developing effective chemical reactions that can be applied on various types of molecules such as organics like napthaquinones, thiazolidinediones, chlorofluoropyrroles, anthrapyrazole rings, pyranols, etc.. These new substances will find use in diverse areas including medicine, biology, electronics, sensors, fuel cells, polymer electrodes, dyes, pigments, pesticides, herbs, fragrance agents, food products, cosmeceuticals, paints, coatings, adhesives, lubricants, plasticizers, rubbers, ceramics, electronic devices, drug delivery systems, nanocomposites, and other applications where these novel structures hold promise.
Method used
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Abstract
The invention relates to a method for preparing a tetrahydrobenzo[b][1,8]naphthyridine derivative. Specifically, the invention provides the method for preparing the tetrahydrobenzo[b][1,8]naphthyridine derivative from an o-azidobenzaldehyde derivative and an aza 1,6-eneyne derivative under the catalysis of metal and acid. By adopting the method provided by the invention, a transition metal catalyst is used and the tetrahydrobenzo[b][1,8]naphthyridine derivative, which is difficult to obtain by other methods and has a multiplex-ring structure, is obtained by adopting simple and easy-to-obtain raw materials through simple operation steps.
Description
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Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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