Synthetic method for bifenazate

A technology of bifenazate and a synthesis method, applied in directions such as organic chemistry, can solve the problems of high impurity content of bifenazate, reducing the purity of bifenazate, poor removal effect of impurities, etc., and achieve the effect of improving purity

Active Publication Date: 2019-07-09
绍兴上虞新银邦生化有限公司
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The purpose described in this patented technology helps remove unwanted substances from an organic compound that forms part or all during its production process. This results in higher quality final products with fewer harmful residues than traditional methods used for producing these chemicals.

Problems solved by technology

This patented technical problem addressed in this patents relating to improving pesticidal compositions containing specific substances like benzimidazole or its salts such as nicotinilboreaptablenisporthritonitorone dipropylcarbonothiotropicaglate). These agents have been developed but they still require complicated methods for their production due to residual contamination during storage.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Synthetic method for bifenazate
  • Synthetic method for bifenazate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1 is a kind of bifenazate synthetic method disclosed by the present invention, and the specific synthetic section is as follows:

[0044] S1. Nitrification section: Mix and react 4-hydroxybiphenyl solution and toluene solution. The mass / number ratio of 4-hydroxybiphenyl solution and toluene solution is 1:4. After heating up to 70°C, gradually add HNO3 solution dropwise and keep warm React for 1h to obtain a nitration reaction solution;

[0045] S2. Methylation section: Mix the nitration reaction solution and anhydrous sodium carbonate powder for reaction, then add dimethyl carbonate solution dropwise, and keep it warm for 8 hours; add liquid alkali to the mixed solution, and remove water when the pH of the water layer is ≥ 11 layer, to obtain the methylation reaction solution;

[0046] S3. Hydrogenation section: inject hydrogen gas into the methylation reaction liquid, and react under the catalysis of Raney nickel, the reaction temperature is 55°C, and the re

Embodiment 2

[0062] Embodiment 2 is different from Embodiment 1 in that steps d, e, and f of S6 in Embodiment 1 are deleted.

Embodiment 3

[0063] Embodiment 3, the difference from embodiment 1 is to delete the d and e processes of S6 in embodiment 1, and directly put the first bifenazate filter cake produced in the c process into the double cone dryer in the f process Drying in medium to obtain finished product.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a synthetic method for bifenazate. The method comprises the following specific synthetic sections: step 1, performing nitration: mixing a 4-hydroxybiphenyl solution and a toluene solution under stirring for a reaction, and adding a HNO3 solution dropwise for a reaction to obtain a nitration reaction solution; step 2, performing methylation: mixing the nitration reaction solution and anhydrous sodium carbonate powder for a reaction, and adding a dimethyl carbonate solution dropwise for a reaction to obtain a methylation reaction solution; step 3, performing hydrogenation: throwing the methylation reaction solution, hydrogen gas, and Raney nickel into a reaction kettle for a reaction to obtain a hydrogenation reaction liquid; step 4, performing hydrazination: performing a primary hydrazination reaction, performing a secondary hydrazination reaction, performing filter pressing, performing a tertiary hydrazination reaction, and performing secondary filter pressingto obtain a condensation reaction liquid; step 5, performing condensation: mixing a third hydrazine compound, an ethyl acetate solution and an isopropyl chloroformate solution for a reaction to obtaina bifenazate mixed liquid; and step 6, performing purification: performing desolvation, performing crystallization, performing centrifugation, performing washing, performing secondary centrifugation,and performing drying to obtain the finished bifenazate. The method provided by the invention has the effect of improving purity of the bifenazate product.

Description

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Owner 绍兴上虞新银邦生化有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products