Preparation method of aryl borate

[0032] The invention provides a preparation method of aryl borate, which is characterized in that it comprises the following steps: in the presence of a water-soluble free radical initiator, water is used as a solvent, and arylsulfonyl chloride and biboronic acid pinacol ester are used as The raw materials are reacted to obtain aryl borate.

[0033] According to the preparation method of an aryl borate according to the present invention, further preferably, the arylsulfonyl chloride is phenylsulfonyl chloride, p-tolylsulfonyl chloride, o-tolylsulfonyl chloride or m-tolylsulfonyl chloride acid chloride.

[0034] According to the preparation method of an aryl borate ester described in the present invention, the water-soluble free radical initiator is a water-soluble azo free radical initiator.

[0035] According to the preparation method of an aryl borate ester described in the present invention, further preferably, the water-soluble azo radical initiator is selected from 2,2'-azo

[0043]Add 100ml of water, 0.1mol of benzenesulfonyl chloride, 0.1mol of biboronic acid pinacol ester into the reaction bottle, stir well, then add 0.01mol of 2,2'-azobis(2-methylpropylamidine) disalt salt, slowly raise the temperature to 50°C, keep the reaction at this temperature for 10h, the whole reaction process is in a stirring state, after the reaction, slowly cool the system to room temperature, extract 3 times with ethyl acetate, collect the organic phase , distilled under reduced pressure, and dried in vacuo to obtain a white solid phenylboronic acid pinacol ester with a yield of 88.1% and a purity of 95.6%.

[0045] Add 100ml of water, 0.1mol of benzenesulfonyl chloride, 0.2mol of biboronic acid pinacol ester to the reaction flask, stir well, then add 0.01mol of 2,2'-azobis[2-(2-imidazoline-2- Base) propane] dihydrochloride, slowly raise the temperature to 100°C, keep the temperature for 5h, the whole reaction process is in a stirring state, after the reaction, slowly cool the system to room temperature, use dichloromethane to extract The organic phase was collected three times, distilled under reduced pressure, and dried in vacuo to obtain a white solid phenylboronic acid pinacol ester with a yield of 93.5% and a purity of 95.1%.