Graphene oxide composite microspheres, preparation method thereof and application of graphene oxide composite microspheres in bisphenol compound detection

[0027] In another specific embodiment of the present invention, the preparation method of the above-mentioned graphene oxide composite microspheres is provided, and the preparation method comprises:

[0028] S1. Polystyrene microspheres are treated with polyelectrolyte, so that the surface of the microsphere template is covered with more charges to facilitate the following assembly; specifically, polystyrene microspheres are added to positively charged polydiallyl In base dimethyl ammonium chloride, carry out centrifugal washing after stirring;

[0029] S2, adding the polystyrene microspheres obtained through the treatment in step S1 into negatively charged sodium polystyrene sulfonate, continuing to stir and washing with centrifugal water;

[0030] S3. Alternately assembling graphene oxide and polydiallyldimethylammonium chloride on the polystyrene microspheres obtained in step S2.

[0031] In yet another specific embodiment of the present invention, in the step S1, the mass vo

[0048] The preparation of embodiment 1 graphene oxide composite microsphere

[0049] (1) Put 100mg polystyrene microspheres in 30ml polydiallyldimethylammonium chloride (2mg / ml, M w 400000~500000), stirred for 2 hours, centrifuged and washed with water;

[0050] (2) The polystyrene microspheres obtained by step (1) are placed in 30ml sodium polystyrene sulfonate (2mg / ml, M w 70000), stirred for 2 hours, centrifuged and washed with water;

[0051] (3) Graphene oxide (solution concentration is 1 mg / ml) and polydiallyl dimethyl ammonium chloride (solution concentration is 2 mg / ml) are carried out on the polystyrene microspheres obtained through step (2) treatment ,M w (400000~500000) alternately assemble 5 layers of graphene oxide / polystyrene core-shell microspheres, which are used as adsorbents for dispersed solid-phase microextraction materials. The particle size of graphene oxide / polystyrene core-shell microspheres is uniform, about 3 μm.

[0052] The preparation of embodiment 2 graphene oxide composite microspheres

[0053] (1) Put 100mg polystyrene microspheres in 40ml polydiallyldimethylammonium chloride (2mg / ml, M w 400000~500000), stirred for 2 hours, centrifuged and washed with water;

[0054] (2) the polystyrene microspheres obtained by step (1) are placed in 40ml sodium polystyrene sulfonate (2mg / ml, M w 70000), stirred for 2 hours, centrifuged and washed with water;

[0055] (3) Graphene oxide (solution concentration is 1 mg / ml) and polydiallyl dimethyl ammonium chloride (solution concentration is 2 mg / ml) are carried out on the polystyrene microspheres obtained through step (2) treatment ,M w (400000~500000) alternately assemble 5 layers of graphene oxide / polystyrene core-shell microspheres, which are used as adsorbents for dispersed solid-phase microextraction materials.