Method of synthesis of tetradentate amide macrocycle ligand and its metal-complex

[0019]With reference to FIGS. 1-7, the new methodology of synthesizing tetradentate amide based macrocyclic ligand and its iron complex can be described. The molecular structure of tetradentate amide based macrocyclic ligand 1 and its iron complex 2 are shown in FIG. 1. Tetradentate amide based macrocyclic ligand 1 was synthesized using standard reactions of amine and acid chlorides with high yield. Ligand 1 was used to develop its iron complex 2, which is soluble and stable in aqueous solution. Iron complex 2 activates H2O2 in water under ambient conditions and acts as an excellent oxidation catalyst.

[0020]A new tetradentate amide based macrocyclic ligand 1 and its Fe-complex 2 are synthesized according to FIG. 2. More specifically, O-phenylenediamine (3 gm, 27.8 mmol) and triethylamine (27.8 mmol, 3.8 mL) were dissolved in 47 mL of dry THF (dried over sodium and benzophenone). Di-tert-butyl-carbonate (6.05 gm, 27.8 mmol) was dissolved in 50 mL of THF. Both the solutions were combined