The invention provides paste having the effects of clearing away heart fire and refreshing. The paste is prepared from the following raw materials of lily bulbs, Chinese yams, poria cocos, rhizoma polygonati, semen platycladi, grassleaf sweetflag rhizomes, glue of tortoise plastron, deerhorn glue, colla corii asini, jujube flesh, honey and yellow wine. The paste provided by the invention is simple to make, convenient to store, natural in raw materials and good in mouth feel, has obvious effects of clearing away heart fire, refreshing, invigorating the spleen, tonifying the lung, nourishing yin, soothing the nerves and the like, and has broad applicability and business values.