2 results about "Dried blood spot" patented technology

The invention discloses a kit for detecting valproic acid drug concentration in dry blood spots. The kit comprises a kit body, a first container, a calibrator card and a quality control card, whereinthe calibrator card is a blood spot collection card fixed with a group of valproic acid dry blood spot samples as dry blood spot calibration points, and the number of the dry blood spot calibration points is at least six, the quality control material card is a blood spot collection card fixed with at least one group of valproic acid dry blood spot samples as dry blood spot quality control points,the number of each group of dry blood spot quality control points is at least three, the first container is filled with an internal standard extracting solution, and an internal standard adopts isotopic substituted valproic acid. The invention further discloses a detection method of the kit. The kit provided by the invention has advantages of simple preparation of reagents, less required amount ofsamples, convenience in storage and transportation, rapid pretreatment, short analysis period, lower cost and the like, and is suitable for popularization in clinical conventional detection.

The invention discloses a dried blood spot quality control product for neonatal screening and a preparation method thereof. The dried blood spot quality control product comprises a filter paper carrier, the filter paper carrier is infiltrated with a blood working solution, and the blood working solution takes Chinese species blood as a matrix solution, and is formed by mixing the matrix solution and an extracting solution according to a certain proportion. The extracting solution comprises amino acid, free acyl carnitine, lysophosphatidylcholine, orotic acid and succinylacetone. The dried blood spot quality control product disclosed by the invention has good uniformity and stability, and can be used as an indoor quality control product in a neonatal screening project; and the preparation process is simple and convenient to operate.