4 results about "Pathogenic microorganism" patented technology

The invention provides a sputum pathogenic microorganism metagenome de-homing extraction system and method. The system comprises a sputum liquefaction module for liquefying sputum, a de-homing modulefor removing a host, and a nucleic acid extraction module used for extracting nucleic acid from which the host is removed. According to the invention, a sputum sample can be treated in advance in combination with a host removal system, and nucleic acid extraction is carried out in combination with an extraction kit. The complete characteristics of pathogenic microorganisms in sputum are reserved as much as possible while sputum liquefaction is met, so that the sputum liquefaction and removal of human-derived hosts are realized, and genomes of microorganisms are highly reserved.

The invention relates to a method and a system for semi-closely processing medical sewage. The method comprises the following steps: (1) wet type grinding; (2) sterilization by a chlorine method; (3) removal of residue disinfectant; (4) primary sedimentation; (5) aerobic bio-chemical processing of activated sludge; (6) secondary sedimentation, wherein the steps of (1) and (2) and the transfer of the sewage from the step (1) to the step (2) are carried out in a closed state. The system comprises wet type grinding equipment, a sterilization pond, a disinfectant removing pond, a primary sedimentation pond, an activated sludge pond and a secondary sedimentation pond, which are connected in sequence, wherein the wet type grinding equipment, the sterilization pond, and a sewage transfer device between the wet type grinding equipment and the sterilization pond all adopt the closed structure. The method and the system have the advantages of the realization of microorganism safety, unsusceptible occurrence of spreading risk of pathogenic microorganisms, relatively less investment, and convenient operation and maintenance.

The invention provides a cow interdigital skin explant model construction method, and belongs to the technical field of skin explant models. The model construction method comprises the following steps: immersing the interdigital skin of the dairy cow into a transportation culture medium for transportation, cleaning the interdigital skin of the dairy cow by using a washing culture medium after transportation is completed, and culturing the cleaned interdigital skin of the dairy cow in a cell chamber containing a tissue culture medium to complete model construction; and finally, carrying out feasibility evaluation on the cow interdigital skin explant model. The constructed 3D dairy cow interdigital skin model conforms to experimental animal 3R principles of reduction, substitution, optimization and the like, meanwhile, the constructed model can maintain good tissue structure integrity, the dairy cow interdigital skin in-vivo environment is fully simulated, and the method has great significance in deep research of dairy cow interdigital skin pathogenic microorganism invasion action mechanism.