The invention relates to an application of cellular
repressor of E1A-stimulated
gene (CREG)
protein, and in particular to an application of the CREG
protein or an active fragment thereof in preparingmedicines for preventing and / or treating
overweight,
obesity,
insulin resistance, hyperlipemia and related diseases thereof. The invention also relates to an application of a recombinant vector or recombinant cells of the CREG
protein or the active fragment thereof in preventing and / or treating
overweight,
obesity,
insulin resistance, hyperlipemia and related diseases thereof.