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1 results about "Repressor" patented technology

In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers. A DNA-binding repressor blocks the attachment of RNA polymerase to the promoter, thus preventing transcription of the genes into messenger RNA. An RNA-binding repressor binds to the mRNA and prevents translation of the mRNA into protein. This blocking of expression is called repression.

Medicinal application of CREG protein in preventing or treating overweight, obesity and related diseases thereof

InactiveCN107693775AImprove the level ofRaise or lower levelPeptide/protein ingredientsMetabolism disorderDiseaseOverweight
The invention relates to an application of cellular repressor of E1A-stimulated gene (CREG) protein, and in particular to an application of the CREG protein or an active fragment thereof in preparingmedicines for preventing and / or treating overweight, obesity, insulin resistance, hyperlipemia and related diseases thereof. The invention also relates to an application of a recombinant vector or recombinant cells of the CREG protein or the active fragment thereof in preventing and / or treating overweight, obesity, insulin resistance, hyperlipemia and related diseases thereof.
Owner:GENERAL HOSPITAL OF THE NORTHERN WAR ZONE OF THE CHINESE PEOPLES LIBERATION ARMY
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