Cosmetic product containing GSH lipid nano-emulsion
A technology of lipid nano and cosmetics, which is applied in the direction of cosmetics, cosmetic preparations, dressing preparations, etc., can solve the problems such as glutathione reports that have not been seen, so as to improve the transdermal absorption capacity, promote skin absorption, enhance Applied effect
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Embodiment 1
[0032] Embodiment 1: Cosmetics containing GSH lipid nanoemulsion
[0033] 1. Composition:
[0034]
[0035] 2. Preparation method:
[0036] 1) Dissolve phospholipids in 70ml of chloroform-n-hexane solution (chloroform:n-hexane, 5:7, v / v), dissolve glutathione in 10ml of distilled water, stir well, mix the two solutions, and ultrasonicate , the obtained emulsion is freeze-dried to obtain glutathione-phospholipid complexes;
[0037] 2) Mix glutathione-phospholipid complex, caprylic acid / capric glyceride, polyglycerol oleate, Tween 80, polyoxyethylene castor oil, polyethylene glycol caprylic acid / capric glyceride, at 8000rpm Under high-speed shearing, until there is no visible solid in the system;
[0038] 3) Add glycerin and water to the product of step 2), and shear at a high speed at 12000 rpm to obtain colostrum, which is processed by a high-pressure homogenizer at a pressure of 800 bar and circulated 5 times to obtain a transparent and clear cosmetic.
Embodiment 2
[0039] Embodiment 2: Cosmetics containing GSH lipid nanoemulsion
[0040] 1. Composition:
[0041]
[0042]
[0043] 2. Preparation method:
[0044] 1) Dissolve phospholipids in 50ml of chloroform-n-hexane solution (chloroform:n-hexane, 5:7, v / v), dissolve glutathione in 10ml of distilled water, stir well, mix the two solutions, and sonicate , the obtained emulsion is freeze-dried to obtain glutathione-phospholipid complexes;
[0045] 2) Mix glutathione-phospholipid complex, caprylic acid / capric glyceride, Span 80, polyglycerol oleate, Tween 80, and polyoxyethylene castor oil, and shear at a high speed at 12000rpm to the system No solids visible to the naked eye;
[0046] 3) Add glycerin and water to the product of step 2), shear at 8000rpm at high speed to obtain colostrum, which is processed by a high-pressure homogenizer at a pressure of 1200bar, and circulated 7 times to obtain a transparent and clear cosmetic.
Embodiment 3
[0047] Embodiment 3: Cosmetics containing GSH lipid nanoemulsion
[0048] 1. Composition:
[0049]
[0050] 2. Preparation method:
[0051] 1) Dissolve phospholipids in 50ml of chloroform-n-hexane solution (chloroform:n-hexane, 5:7, v / v), dissolve glutathione in 15ml of distilled water, stir well, mix the two solutions, and ultrasonicate , the obtained emulsion is freeze-dried to obtain glutathione-phospholipid complexes;
[0052] 2) Mix glutathione-phospholipid complex, caprylic / capric glycerides, Span 80, polyglyceryl oleate, Tween 80, polyethylene glycol caprylic / capric glycerides at high speed at 10000rpm Cut until there is no visible solid in the system;
[0053] 3) Glycerin and water are added to the product of step 2), and the colostrum is obtained by high-speed shearing at 10,000 rpm. The colostrum is processed by a high-pressure homogenizer at a pressure of 2,000 bar and circulated 10 times to obtain a transparent and clear cosmetic.
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