Pharmaceutical composition for treating Alzheimer's disease by combination of Chinese and Western medicines and preparation method of pharmaceutical composition
A combined treatment and composition technology, applied in the field of medicine, can solve the problems of inability to delay disease development, liver and kidney toxicity of western medicine, and insignificant curative effect, and achieve the effects of low side effects, broad medical application prospects, and short course of treatment.
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Embodiment 1
[0020] A preparation method of a pharmaceutical composition for treating Alzheimer's disease in combination with Chinese and western medicine, comprising the steps of:
[0021] S1: Make 20 parts of Poria cocos, 10 parts of lavender, 10 parts of white peony, 12 parts of Shichangpu, 12 parts of hemp seed, 12 parts of Acanthopanax, and 12 parts of buffalo horn, add water to decoct 3 times, and filter , combine the filtrates, concentrate the filtrates under reduced pressure to 3 times the amount of raw materials, add ethanol with a mass concentration of 60-70%, stand still for 24-48h, remove the supernatant, concentrate and dry the precipitate under reduced pressure, and pulverize into fine powder for later use;
[0022] S2: Grinding 1.4 parts of nimodipine and 1.5 parts of piracetam into fine powder 2;
[0023] S3: Mix the fine powder 2 obtained in step S2 with the fine powder 1 obtained in step S1, add sodium carboxymethyl starch, dextrin, and magnesium stearate, mix evenly, granul
Embodiment 2
[0025] A preparation method of a pharmaceutical composition for treating Alzheimer's disease in combination with Chinese and western medicine, comprising the steps of:
[0026] S1: Make 25 parts of Poria cocos, 15 parts of lavender, 15 parts of white peony, 14 parts of Shichangpu, 14 parts of hemp seed, 14 parts of Acanthopanax, and 13 parts of buffalo horn, add water to decoct 3 times, and filter , combine the filtrates, concentrate the filtrates under reduced pressure to 3 times the amount of raw materials, add ethanol with a mass concentration of 60-70%, stand still for 24-48h, remove the supernatant, concentrate and dry the precipitate under reduced pressure, and pulverize into fine powder for later use;
[0027] S2: Grinding 2 parts of nimodipine and 2.5 parts of piracetam into fine powder 2;
[0028] S3: Mix the fine powder 2 obtained in step S2 with the fine powder 1 obtained in step S1, add sodium carboxymethyl starch, dextrin, and magnesium stearate, mix evenly, granulat
Embodiment 3
[0030] A preparation method of a pharmaceutical composition for treating Alzheimer's disease in combination with Chinese and western medicine, comprising the steps of:
[0031] S1: Make 30 parts of Poria cocos, 20 parts of lavender, 20 parts of white peony, 15 parts of Shichangpu, 15 parts of hemp seed, 15 parts of Acanthopanax, and 15 parts of buffalo horn, add water to decoct 3 times, and filter , combine the filtrates, concentrate the filtrates under reduced pressure to 3 times the amount of raw materials, add ethanol with a mass concentration of 60-70%, stand still for 24-48h, remove the supernatant, concentrate and dry the precipitate under reduced pressure, and pulverize into fine powder for later use;
[0032] S2: Grinding 3.2 parts of nimodipine and 3.5 parts of piracetam into fine powder 2;
[0033] S3: Mix the fine powder 2 obtained in step S2 with the fine powder 1 obtained in step S1, add sodium carboxymethyl starch, dextrin, and magnesium stearate, mix evenly, granul
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