Photoelectrochemical sensing device and method for analyzing m5C and m6A in RNA

A technology of photoelectrochemistry and sensing devices, applied in the direction of material electrochemical variables, measuring devices, analyzing materials, etc., can solve problems such as the influence of detection results and insufficient stability of installation, so as to facilitate popularization and use, ensure sealing, and ensure stability Effect

Pending Publication Date: 2021-10-22
ARMY MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology provides an improved chemical sensor with two stable parts: one part called the internal limitation axis (ILC), another part called a reset spring or a push-block. These technical features help make it safer and more accurate than previous designs for detectors made up from multiple components.

Problems solved by technology

This patented technical problem addressed by these two types of sensor systems described earlier relates how they can be applied safely while analyzing samples containing nucleic acids such as miRNAs (micro ribonucleas) from small tissue fragments collected with microscopes. Current solutions involve expensive instruments that require trained staffs who may also damage their sensitive components due to impact caused by shock/shake.

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  • Photoelectrochemical sensing device and method for analyzing m5C and m6A in RNA
  • Photoelectrochemical sensing device and method for analyzing m5C and m6A in RNA
  • Photoelectrochemical sensing device and method for analyzing m5C and m6A in RNA

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Embodiment Construction

[0027] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0028] see Figure 1-8 , an embodiment provided by the present invention: a photoelectrochemical sensing device for m5C and m6A analysis in RNA, including a support assembly 1, a sealing assembly 2, a glass detection box 3, an upper cover 4, a photoelectrochemical sensor 5 and a pole piece 6. The support assembly 1 includes a base 11, a connecting rod 12, a groove 13, a first mount 14, a second mount 15, a chute 16, a limit shaft 17, a first return spring 18, a t

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Abstract

The invention discloses a photoelectrochemical sensing device and method for analyzing m5C and m6A in RNA, the photoelectrochemical sensing device comprises a supporting assembly, a sealing assembly, a glass detection box, an upper cover, a photoelectrochemical sensor and a pole piece. The sensing method comprises the following steps: step 1, equipment connection; step 2, detection preparation; step 3, detecting and recording. Through cooperation of a limiting shaft, a first reset spring, a trapezoidal groove and a push block in the supporting assembly, the stability of the photoelectrochemical sensing device during use is guaranteed, meanwhile, the height of the electrochemical sensing device can be adjusted, and use is convenient; a first gear, a second reset spring, an ejector rod, a pawl, a spring piece, a second gear, a torsion spring, a sealing belt and a second limiting groove in the sealing assembly are matched to form a sealing structure, so that the sealing performance of the electrochemical sensing device in use is conveniently ensured, and the influence of an external environment on detection is reduced; the method is simple, comprehensive and convenient to popularize and use.

Description

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Claims

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Application Information

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Owner ARMY MEDICAL UNIV
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