3 results about "Diabetic nephropathy" patented technology

The invention discloses an enema preparation for treating diabetic nephropathy, prepared from the following medicinal raw materials in parts by weight: 20-40 parts of round cardamom, 20-40 parts of juniper, 20-40 parts of salvia miltiorrhiza, 20-40 parts of bezoar, 5-15 parts of bear gall, 10-15 parts of Chinese violet and 2-5 parts of senna leaf. The preparation method comprises the following steps of: taking the medicinal raw materials, mixing, immersing in water, decocting for 60-90 minutes, and filtering to obtain the decoction, namely the enema preparation for treating diabetic nephropathy. The enema preparation is applied as follows: about 150g of decoction is used for enema once before sleep at night, one course of treatment lasts for 20 days, and enema is performed twice per day for patients with serious symptoms. The enema preparation disclosed by the invention has the efficacies on expelling toxin, promoting urination and promoting the subsidence of swelling, has the advantages of definite curative effect, low price, easiness of preparation, acceptability of patients and the like, can delay the development of diabetic nephropathy, can become an important measure for conservative treatment in the azotemia stage of diabetic nephropathy, and has very high clinical use value.

The present invention relates to a novel imidazopyridine derivative, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient for preventing or treating cancer. The novel imidazopyridine derivative according to the present invention, a stereoisomer thereof and a pharmaceutically acceptable salt thereof can effectively inhibit cancer-related kinases, are excellent in inhibiting proliferation of cancer cells in a cancer cell line, and effectively inhibit proliferation of cancer cells (cancer cell apoptosis) in a cancer cell heterograft model, and thus can be useful as a pharmaceutical composition containing the same as an active ingredient for preventing or treating cancer.

Also, the novel imidazopyridine derivative according to the present invention, the stereoisomer thereof, and the pharmaceutically acceptable salt thereof can effectively inhibit Src and Fyn, thereby being useful as a pharmaceutical composition for preventing or treating the Src and Fyn related diseases, and in particular, have been confirmed to be useful in diabetic nephropathy in animal model experiments. Therefore, the compound of the present invention can be effective as a pharmaceutical composition containing the same as an active ingredient for preventing or treating diabetic nephropathy.

The invention discloses a drainage type kit for early diagnosis of diabetic nephropathy, which comprises a kit body, a constant temperature block is fixedly connected in the kit body, the inner wall of the kit body is connected with a plurality of circularly distributed isolation detection components, and the isolation detection components can be separated and detected through the cooperation of the constant temperature block and a negative pressure drainage component. The sealing detection mode can be effectively achieved, serum in the serum storage tank can make contact with the sealed isolation detection assembly for detection under drainage of the negative pressure drainage assembly, it is effectively avoided that the serum and detection test paper are exposed to the external environment in the detection process, the detection error is reduced, and the reliability of the detection result is improved; the detection steps are effectively simplified, the detection difficulty is reduced, the kit is convenient for common personnel to operate and use, and the popularization of the kit body is effectively promoted.