The invention belongs to the technical field of
medical biology and discloses a composition for resisting
propionibacterium acnes and regulating
skin micro-
ecology. The composition comprises the following components (by weight): 0.5-3 parts of
nisin, 0.1-2 parts of
polylysine, 0.1-2 parts of
cordycepin, 0.1-1 part of
lysozyme, 10-50 parts of water and 0.5-4 parts of a pH
regulator. The compositionhas a remarkable antagonistic effect on the growth of
propionibacterium acnes and
staphylococcus aureus, and can weaken the film-forming growth of
propionibacterium acnes, so that the
skin invasiveness of
propionibacterium acnes is weakened, the occurrence and development of acnes are intervened, and then the effect of preventing and treating acnes is achieved. According to the composition, the microbial
flora on the surface of the
skin is regulated to help recover the micro-ecological balance of the skin; and most of the main components of the composition can be degraded into amino acids, sothat a part of
nutrient matrix can be provided for
skin repair. The composition can be added into a skin micro-
ecology regulating preparation, an anti-
acne preparation or an
acne removing preparation.