The invention discloses a system and a method for processing multi-transponder programs by an integrated conditional access module; the system comprises a tuner, an FPGA, a controller, an intelligent card and a modulator; wherein the output end of the tuner is connected with the input end of the FPGA, the FPGA is connected with the controller, the controller is connected with the intelligent card, and the output end of the FPGA is connected with the modulator; the controller is used for analyzing program identifier values of the authorization control information and the authorization management information, sending effective data to the intelligent card to complete authorization and obtain control words, and sending the control words of programs to the FPGA in real time, and the FPGA is used for descrambling video and audio data; an integrated CAM board card is used, four repeaters and three intelligent cards are additionally arranged, decryption and descrambling of 56 sets of encrypted programs on the four repeaters can be completed at the same time, the processing capacity of the digital forwarding all-in-one machine is improved, and the size occupied by the decryption part of the all-in-one machine is greatly reduced.