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2 results about "Sodium iodide" patented technology

Sodium iodide (chemical formula NaI) is an ionic compound formed from the chemical reaction of sodium metal and iodine. Under standard conditions, it is a white, water-soluble solid comprising a 1:1 mix of sodium cations (Na⁺) and iodide anions (I⁻) in a crystal lattice. It is used mainly as a nutritional supplement and in organic chemistry. It is produced industrially as the salt formed when acidic iodides react with sodium hydroxide.

Synthesis method of compound for protein fluorescent labeling

The invention discloses a synthesis method of a compound for protein fluorescent labeling and relates to the technical field of biomacromolecule fluorescent labeling. The synthesis method comprises the following steps of 1, reaction 1: heating 1.2-1.5 equivalent of a compound I and 1 equivalent of a compound II in 1.5-3.5 equivalent of acetic anhydride with stirring for 0.5-1h to obtain an intermediate III, and 2, reaction 2: heating 1 equivalent of the intermediate III and 1.1-1.5 equivalent of sodium iodide in an organic solvent 2 to a temperature of 40-70 DEG C, and carrying out reflux for 2-24h to obtain a desired product IV which is a water-soluble fluorescent compound. A cyanine compound is introduced with multiple hydrophilic sulfonic acid groups so that water solubility is improved. A distance between a connection locus and a fluorescent group is further reduced so that probe rigidity is improved and thus the problem that the existing protein fluorescent probe has nonuniform hydrophobic ends and hydrophilic ends and has long length of a probe connection group.
Owner:顾新华
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