11 results about "Sulfonic acid" patented technology

This invention relates to bioadhesive compositions, which are particularly, but not exclusively, useful for making medical electrodes and to medical electrodes based on such compositions. A first bioadhesive composition comprises: 10 (i) 28-60 wt % of a copolymer comprising repeating units derived from one or more monomers selected from olefinically unsaturated sulphonic acids and repeating units derived from one or more olefinically unsaturated carboxylic acids, the ratio by weight of the sulphonic acid units to the carboxylic acid units being from 30:1 to 1:1; 15 (b).

The invention relates to a preparation method of rice hull carbon based solid sulfoacid. The preparation method of the rice hull carbon based solid sulfoacid which can be applied to various acid catalyzed reactions. The preparation method of the rice hull carbon based solid sulfoacid includes the following steps: mixing rice hulls with concentrated sulfuric acid, heating and stirring the mixture, conducting partial carbonization, obtaining solid materials, filtering, water washing and alcohol washing, and obtaining the carbon based solid sulfoacid. The sulfoacid preparation method of the rice hull carbon based solid is simple in operation, short in reaction time, high in density of obtained carbon based solid sulfoacid and capable of bring convenience for industrial implementation and the like, and providing a novel method.

The invention discloses a novel sorafenib tosylate polycrystalline form A and a preparation method thereof. A DSC spectrum of the crystal form comprises a transition peak at 198.0-207.5 DEG C and a melting decomposition peak at 238.5-247.5 DEG C. The invention also discloses a method for preparing the sorafenib tosylate (I) polycrystalline form A from sorafenib free base and p-toluenesulfonic acid in a mixed solvent of alcohol and water. The method has the advantages of good repeatability, simple operation, high product yield, high purity, and suitability for industrialized productions.

The invention relates to a phosphorus-free corrosion and scale inhibitor applicable to high-chlorine high-concentration-multiple circulating cooling water and a preparation method of the phosphorus-free corrosion and scale inhibitor, belonging to the technical field of water treatment. The technical problem to be solved by the invention is to provide the phosphorus-free corrosion and scale inhibitor with low toxicity, chloride resistance and low cost for high-concentration-multiple circulating cooling water containing high-concentration chloride ions. The phosphorus-free corrosion and scale inhibitor is prepared from the following raw materials in parts by weight: 3 to 5 parts of zinc sulfate, 4 to 7 parts of sodium gluconate, 2 to 4 parts of sodium molybdate, 0.5 to 2 parts of benzotriazole, 5 to 9 parts of and acrylic acid-2-acrylamide-2-methylpropanesulfonic acid copolymer, 7 to 12 parts of polyepoxysuccinic acid and 3 to 5 parts of hydrolyzed polymaleic anhydride. Compared with similar corrosion and scale inhibitors, the phosphorus-free corrosion and scale inhibitor for high-concentration-multiple circulating cooling water provided by the invention has the advantages of strongtargeting performance, low toxicity, chloride resistance, low cost, simple operation, convenience, rapidness, environmental friendliness, safety, high efficiency and the like.

The invention discloses a method for electroplating a goldfinger with a thick gold layer. The method comprises the following processes: a, using copper-clad plate to etch an outer circuit, and forming a goldfinger leading wire; b, coating a coating material so as to form a gold-plating finger area; c, carrying out electronickelling on the gold-plating finger; d, electrogilding on the nickel layer of the gold-plating finger area; and e, removing the goldfinger leading wire and forming a solder mask, wherein a nickel aminosulfonate electroplating liquid is used in the process c for the electronickelling of the gold-plating finger area; and a nickel sulfonic acid electroplating liquid is a mixed solution of 300-600g/L nickel aminosulfonate, 20-50g/L boric acid and 30-70g/L nickel chloride. According to the method, the nickel aminosulfonate electroplating liquid is selected for the electronickelling of the gold-plating finger area, so that the electronickelling efficiency is high, the surface of the electronickelling layer is smooth and does not have residual stress, and the subsequent gold layer can be stably plated without gold throwing; and the goldfinger plated by the method is particularly suitable for electroplating gold layers with the thickness above 30 microinches, the nickel layer can be effectively prevented from being exposed, and the quality of the produced goldfinger can be greatly improved.

The invention discloses an epoxy group containing polysilsesquioxane sulfonate, and a preparation method and applications thereof. The preparation method comprises following steps: a, a mercapto trialkoxysilane monomer is added into an aqueous solution containing an anionic surfactant and an alkali catalyst for reaction; b, after reaction in step a, with stirring, under ultraviolet lamp illumination, p-styrene sulfonate, glycidyl methacrylate, and 1-hydroxycyclohexyl phenyl ketone are added successively; c, after reaction in step b, solid liquid separation is carried out so as to obtain a solid product; and d, the solid product obtained in step c is subjected to washing and drying so as to obtain a finished product. According to the preparation method, grafting of the sulfonate and the epoxy groups onto the polysilsesquioxane chains of the epoxy group containing polysilsesquioxane sulfonate is adopted, so that the compatibility with PC is excellent, dispersion is convenient, migrationresistance is achieved, pollution is less, and an extremely low adding amount is capable of improving PC flame resistance grade to be UL94V-0 grade (1.6mm), and the durability is excellent.

The invention discloses a derivative based on rhodamine B and a preparation method and application thereof. The preparation method of the derivative comprises the following steps: under nitrogen protection, adding a dichloromethane solution of D-sphingol into an acetonitrile solution of N-ethyl p-toluenesulfonate of rhodamine B; in the presence of dried potassium carbonate, heating the solution tocarry out a reflux reaction to prepare a coarse product; and concentrating the coarse product and carrying out silicagel column separation to obtain a pure product. A pH titrating experiment verifiesthat in a DMSO/BR(1/99, v/v) system, the derivative does not give out fluorescence in a neutral condition, and the fluorescence intensity at 600 nm is enhanced gradually as the pH is reduced from 7.4to 2.0. The pKa value is 4.32, the pH response range is 2.0-7.4, and a golgiosome weak acidic environment is detected favorably. In addition, a probe has good selectivity, water solubility and low toxicity. An intracellular co-positioning experiment and a golgiosome pH adjusting experiment verify that the derivative can mark the golgiosome specifically in a targeted manner and can detect the pH change of the golgiosome with high sensitivity.

The invention discloses a waterproof material for polystyrene boards and gypsum boards of building walls. The waterproof material is prepared from the following raw materials in parts by weight: 8-10parts of cement clinker, 6-10 parts of quick lime, 10-15 parts of a polyethylene emulsion, 15-20 parts of a paraffin emulsion, 4-8 parts of glass fibers, 3-6 parts of borax, 3-6 parts of sodium alginate, 3-5 parts of a grinding aid, 3-4 parts of sodium methyl silicate, 2-6 parts of hydroxyethyl cellulose, 2-4 parts of sodium tripolyphosphate, 2-4 parts of triethanolamine, 2-3 parts of aluminum potassium sulfate, 2-3 parts of dodecyl ethyoxyl sulphobetaine, 1-3 parts of polyacrylamide, 1-2 parts of calcium lignosulphonate and 50-80 parts of water. During construction, only 1mm of the material needs to be smeared on a polystyrene board wall body and a gypsum board wall body, after air drying, the surface layer of the wall surface is cleaned and polished to be flat, construction is convenient, time and labor are saved, the polystyrene board wall body and the gypsum board wall body treated through the material can completely eradicate the phenomena of alkali efflorescence, falling, moisture regain, mildewing and hollowing of the wall bodies, the service life of the polystyrene board and the gypsum board of the building wall body is greatly prolonged, and the cost is low.

The present invention is directed to cocrystal forms of ((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxcyclopentyl) methyl sulfamate of formula (I). The invention is also directed to methods of making cocrystal forms of ((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl) methyl sulfamate of formula (I). The invention is also directed to the pharmaceutical use of a cocrystal form as an E1 activating enzyme inhibitor, as well as a pharmaceutical composition comprising a cocrystal form. The invention is further directed to a method of treatment comprising administering a cocrystal form of ((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo [2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate of formula (I).