Molluscicide LDS sustained-release granules and preparation method thereof
A technology of chlorinated salicylamine and slow-release granules, which is applied in the field of pesticides, can solve the problems of repeated application, powder scattering, powder easy to flow with the wind, etc., achieve sustained and slow release of drug effect, strong resistance to rain erosion , increase the effect of killing snails
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[0017] Example 1
[0018] Mix 50.0g of chlorinated salicylamine original medicine, 30.0g of soluble starch, 10g of dextrin, 8.5g of magnesium stearate, 0.6g of sodium lauryl sulfonate, and 0.9g of simethicone, and add appropriate amount of water. ,While heating to 60℃~70℃, stir evenly with the aid of a mixer, then extrude and granulate, dry and grind until the particles are finer than the pharmacopoeia sieve 10 mesh and 24 mesh, and the particle size is 10 mesh to 24 mesh Granules are chlorinated salicylamine sustained-release granules.
Example Embodiment
[0019] Example 2
[0020] Combine 50.0 g of chlorinated salicylamine original medicine, 30.0 g of amylose, 8.5 g of sodium carboxymethyl starch, 0.9 g of sodium cetyl trimethyl bromide, 0.6 g of polyoxypropylene polyoxyethylene glyceryl ether, hard Magnesium fatty acid 10.0g, mix well, add appropriate amount of water, stir and heat to 70℃, keep for 30 minutes, after it becomes viscous and moist mass, squeeze granulate, dry through pharmacopoeia sieve, take 10 mesh and 24 mesh The particles in between are chlorinated salicylamine sustained-release granules.
Example Embodiment
[0021] Example 3
[0022] Combine 40.0g of chlorinated salicylamine, 40.0g of amylose, 7.0g of diatomaceous earth, 10.0g of hydroxypropyl methylcellulose, 0.6g of cetyltrimethylammonium chloride, 1.5g of liquid paraffin, two Mix 0.9g methyl silicone oil evenly, add appropriate amount of water, and heat to 70~80℃, stir to make it into a viscous mass, extrude and granulate, dry, pass through a pharmacopoeia sieve, and take between 10 mesh and 24 mesh The particles are the chlorinated salicylamine sustained-release granules.
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