Compound pediatric antipyretic suppository and preparation method thereof
A technology for children and antipyretics, which is applied in the field of pharmacy, can solve problems such as cavities in plugs, stratification of plugs, affecting the quality and safety of drugs, and achieve the effect of improving quality
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Embodiment 1
[0030] prescription:
[0031] Artificial bezoar 100g Acetaminophen 3kg Nanbanlan root extract powder 1kg Polysorbate 80 140g
[0032] Ethylparaben 2.1g Mixed fatty acid glyceride (type 38) 15.67kg 95% ethanol 197.93g
[0033] Preparation method:
[0034] (1) Preparation of Southern Radix Radix Radix Extract Powder Powder:
[0035] Add 1 times the amount of crude drug to the drinking water of Nanbanlangen decoction pieces, soak for 30 minutes. Decoct twice. For the first decoction, add drinking water with 5 times the amount of crude drug, and decoct for 2 hours. For the second decoction, add drinking water with 4 times the amount of crude drug, and decoct for 1.5 hours. During each extraction process, 2 forced cycles were performed, and the time of each forced cycle was 15 minutes. Combine the extracts and filter. Concentrate to a clear paste with a relative density of 1.15-1.25 (60°C), and let it cool. Transfer to an alcohol precipitation tank and add ethanol under stirri
Embodiment 2
[0047] prescription:
[0048] Artificial bezoar 100g Acetaminophen 3kg Nanbanlan root extract powder 1kg Polysorbate 80 140g
[0049] Ethylparaben 2.1g Mixed fatty acid glyceride (type 38) 15.67kg 95% ethanol 197.93g
[0050] Preparation method:
[0051] (1) Preparation of Southern Radix Radix Radix Extract Powder Powder:
[0052]Add 1 times the amount of crude drug to the drinking water of Nanbanlangen decoction pieces, soak for 30 minutes. Decoct twice. For the first decoction, add drinking water with 5 times the amount of crude drug, and decoct for 2 hours. For the second decoction, add drinking water with 4 times the amount of crude drug, and decoct for 1.5 hours. During each extraction process, 2 forced cycles were performed, and the time of each forced cycle was 15 minutes. Combine the extracts and filter. Concentrate to a clear paste with a relative density of 1.15-1.25 (60°C), and let it cool. Transfer to an alcohol precipitation tank and add ethanol under stirrin
Embodiment 3
[0062] prescription:
[0063] Artificial bezoar 100g Acetaminophen 3kg Nanbanlan root extract powder 1kg Polysorbate 80 140g
[0064] Ethylparaben 2.1g Mixed fatty acid glyceride (type 38) 15.67kg 95% ethanol 197.93g
[0065] Preparation method:
[0066] (1) Preparation of Southern Radix Radix Dry Paste Powder:
[0067] Add 1 times the amount of crude drug to the drinking water of Nanbanlangen decoction pieces, soak for 30 minutes. Decoct twice. For the first decoction, add drinking water with 5 times the amount of crude drug, and decoct for 2 hours. For the second decoction, add drinking water with 4 times the amount of crude drug, and decoct for 1.5 hours. During each extraction process, 2 forced cycles were performed, and the time of each forced cycle was 15 minutes. Combine the extracts and filter. Concentrate to a clear paste with a relative density of 1.15-1.25 (60°C), and let it cool. Transfer to an alcohol precipitation tank and add ethanol under stirring to make
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