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2 results about "Colon cancer cell" patented technology

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Cancer that starts in the colon or rectum is often called colorectal cancer. It starts when cells in the colon or rectum grow out of control and crowd out normal cells. This makes it hard for the body to work the way it should.

Nucleic acid aptamer capable of detecting human colon cancer and application thereof in preparing detection preparations

ActiveCN109628455AAccurate diagnosisRapid positioningMaterial analysisDNA/RNA fragmentationChemical synthesisAptamer

The invention discloses a nucleic acid aptamer capable of achieving targeted detection of colon cancer cells and application thereof. The nucleotide sequence of the nucleic acid aptamer is 5'-ACGCTCGGATGCCACTACACGGTTGGGGTCGGGCATGCGTCCGGAGAAGGGCAAACGAGAGGTCACCAGCACGTCCATGAG-3'. The nucleic acid aptamer is good in stability, target molecules can be specifically identified, the immunogenicity in thebody is small, and the target molecules can be easily removed. The aptamer is small in molecular weight and low in preparation cost, can be obtained through chemical synthesis in vitro, and is easy tostore and transport. By adopting the nucleic acid aptamer, various colon cancer cells can be detected, the operation is simple and quick, and early diagnosis, targeted treatment, prognosis and the like of colon cancer are facilitated.

Owner:HUNAN UNIV

Application of pseudostrychnine to inhibiting human colon cancer cells

InactiveCN109908146APrevent proliferationPromote apoptosisOrganic active ingredientsAntineoplastic agentsApoptosisColon cancer cell

The invention belongs to the field of chemical medicine, particularly relates to application of pseudostrychnine to inhibiting human colon cancer cells and aims at providing new application of the pseudostrychnine to inhibiting the human colon cancer cells. The human colon cancer cells are HT-29 cells; the pseudostrychnine can inhibit propagation of the HT-29 cells and promote apoptosis of the HT-29 cells, and the apoptosis rate is in positive correlation with the concentration of the pseudostrychnine; the applied concentration of the pseudostrychnine is 125-1000 mu M. The application of the pseudostrychnine to the inhibiting human colon cancer cells provides a new way for treating human colon cancer and has an important development and application prospect in antitumor drugs.

Application of pseudostrychnine to inhibiting human colon cancer cells

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Owner:山西中医学院中西医结合医院

2 results about "Colon cancer cell" patented technology

Nucleic acid aptamer capable of detecting human colon cancer and application thereof in preparing detection preparations

Application of pseudostrychnine to inhibiting human colon cancer cells

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