The invention discloses a bonding process between a metal base material and a glass base material, which comprises the following steps: coating the surface of the metal base material with a layer of polymer coating, coating the surface of the glass base material with a layer of ink coating, and placing a glue film between the metal base material and the glass base material, and the adhesive film is respectively combined with the polymer coating and the ink coating. According to the bonding process between the metal base material and the glass base material, hydroxyl, carboxyl and isocyanato which are contained on a main chain of thermoplastic polyurethane resin in the adhesive film respectively react with a polymer coating on the surface of the metal base material and an ink coating on the surface of the glass base material; the binding force between the adhesive film and the metal base material and the binding force between the adhesive film and the glass base material are respectively enhanced, so that the connecting strength between the metal base material and the glass base material is improved.