35 results about "Hydroxy group" patented technology

A conjugated diene polymer is provided that contains a conjugated diene-based monomer unit and a group represented by Formula (I) below, at least peaks H, M, and L below being present in a molecular weight distribution curve obtained by gel permeation chromatography measurement, and when the total area of the molecular weight distribution curve is 100%, the total peak area of peak H is 3% to 30%, the total peak area of peak M is 5% to 45%, and the total peak area of peak L is 40% to 80%

(in Formula (I), R¹ and R² independently denote a hydrocarbon group having 1 to 4 carbon atoms, a hydrocarbonoxy group having 1 to 4 carbon atoms, a hydroxy group, or a polymer chain containing a conjugated diene-based monomer unit, m denotes an integer of 0 to 10, and A¹ denotes a polar functional group that does not have an active hydrogen)

Peak H: a peak for which the molecular weight at the peak top is higher than the molecular weight at the peak top of peak M

Peak M: a peak for which, when the molecular weight at the peak top of peak H is MH, the molecular weight at the peak top is 0.6×MH to 0.8×MH

Peak L: a peak for which, when the molecular weight at the peak top of peak H is MH, the molecular weight at the peak top is 0.2×MH to 0.4×MH.

The invention discloses a synthetic method for a chiral quaternary carbon oxazolidinone compound. The synthetic method comprises the following steps: taking o-hydroxy chalcone and azlactone as reactants and synthesizing in a solvent under the catalysis of chiral multifunctional chiral quinine thiourea to obtain a product. The synthetic method disclosed by the invention has the advantages that raw materials are easy to obtain, the reaction conditions are mild, the post-treatment is simple and convenient, the applicable substrate scope is wide, the yield is high, and the enantioselectivity is high; the product obtained by the synthesis method can be used for synthesizing an intermediate of a drug and a pesticide.

The invention relates to a continuous preparation method of flame retardant polyether polyol. The method comprises the following steps: (1) respectively preheating a hydroxy compound and a polyether component, and subsequently adding the preheated hydroxy compound and the polyether component into a reaction tower for reaction according to the mass ratio of (10:90)-(50:50), so as to obtain crude grafted flame retardant polyether polyol; (2) spray-drying the obtained crude grafted flame retardant polyether polyol to obtain the flame retardant polyether polyol. The synthesized flame retardant polyether polyol is good in flame retardancy, and the foam oxygen index of polyurethane foam prepared from the flame retardant polyether polyol is greater than or equal to 28% without an additional flame retardant. Through collision reaction in a tower reactor, the production period is shortened to be 1-2 hours, that is, the production period is shortened by about 50% when being compared with that of the conventional interrupted process; a product is highly dispersed, the viscosity is less than or equal to 3500mpa.s (at 25 DEG C), and the product is free of layering after being preserved for more than 1 year, and is good in storage stability.

The invention discloses a mussel-imitated underwater high-viscosity hydrogel preparation method, which comprises: (1) dissolving chitosan in acetic acid to prepare a chitosan acetic acid solution; (2)adding 3,4-dihydroxyphenylacetic acid, EDC and NHS into the solution prepared in the step (1), adjusting the pH value, and carrying out a reaction for a certain time; (3) dialyzing the solution obtained in the step (2) in water with the pH value of 5, taking the trapped fluid, and carrying out freeze-drying; (4) preparing the sample obtained in the step (3) into a solution; (5) dissolving glucanin water, adding an oxidant, reacting for a certain time in a dark place, and then adding ethylene glycol to terminate the reaction; (6) dialyzing the solution obtained in the step (5) in water, taking the trapped fluid, and carrying out freeze-drying; (7) preparing the sample obtained in the step (6) into a solution; and (8) mixing the solutions obtained in the step (4) and the step (7) to obtainthe hydrogel. According to the preparation method provided by the invention, the prepared hydrogel can be used as an underwater adhesive.

Provided are a resin composition which offers both high transparency and a low linear expansion coefficient and can be used as a material for a dry film, and also a dry film obtained from this composition, an optical waveguide, and a photoelectric composite wiring board. The resin composition for an optical waveguide includes: (A) an epoxy resin constituted by a solid epoxy resin with one or less hydroxyl group in a molecule, and a liquid epoxy resin with one or less hydroxyl group in a molecule; (B) a curing agent with one or less hydroxyl group in a molecule; and (C) a nanosize silica sol, and contains no compound including two or more hydroxyl groups in a molecule as a resin component.

The invention relates to a preparation method of D-p-hydroxyphenylglycine methyl ester. The preparation method comprises the following steps: (1) esterifying: carrying out an esterification reaction on D-p-hydroxyphenylglycine and methanol to obtain D-p-hydroxyphenylglycine methyl ester sulfate, and distilling off methanol and water under reduced pressure, wherein the D-p-hydroxyphenylglycine is added one time, and the methanol is added in batches; and (2) crystallizing the D-p-hydroxyphenylglycine methyl ester. The preparation method can very easily control the reaction endpoint, so that theyield and the quality index of the finished product can be guaranteed to the maximum extent; the preparation method provided by the invention avoids the problems of safety and operation caused by hydrogen chloride gas or thionyl chloride; and in the step of D-p-hydroxyphenylglycine methyl ester crystallization, an alkali metal hydroxide is used for adjusting the pH value of the system without using ammonia water, so that the problem that ammonia ions are difficult to treat is avoided.

Negative-working imageable elements are prepared with radiation-sensitive imageable layers that contain surface-modified silica particles such as fumed silica particles and sol-gel silica particles, that are present in an amount of from about 1 to about 40 weight %, have an average particle size of from about 1 to about 500 nm, have surface hydroxy groups, and have a carbon content of from about 0.5 to about 15 weight % that is derived from surface hydrophobic groups having 1 to 30 carbon atoms. The presence of the surface-modified silica particles provides improved abrasion resistance, reduced tackiness, and various other desired properties.

A method for forming a multilayer coating film is provided. The method includes coating at least one object with an aqueous primer coating composition, an aqueous first colored coating composition, an aqueous second colored coating composition, and a clear coating composition, in that order. The aqueous primer coating composition contains a component (A) which contains a polyolefin resin, a component (B) which contains a polyurethane resin, a curing agent (C) and electrically conductive carbon (D). The aqueous first colored coating composition and aqueous second colored coating composition each contain a core/shell emulsion. The clear coating composition contains a hydroxyl group-containing acrylic resin, a polyisocyanate and a melamine resin. The method improves the appearance, chipping resistance, adhesive properties and low temperature impact properties of a coating film.

The invention discloses a straight-chain liquid AKD surface sizing agent and a preparation method thereof. The straight-chain liquid AKD surface sizing agent is prepared from the following raw materials in parts by weight, 100-200 parts of starch, 1000-2000 parts of water, 4-8 parts of sodium hydroxide, 25-50 parts of a cationic etherifying agent, 5-10 parts of a dilute acid, 15-30 parts of a cationic monomer, 25-50 parts of acrylamide, 1-2 parts of an initiator, 5-10 parts of a dispersing agent, 20-50 parts of an AKD special cationic polymer emulsifier, and 60-150 parts of liquid AKD. The molecular structure of the straight-chain liquid AKD adopted by the invention has a lactone ring structure; reacting under neutral and alkaline conditions; the reaction functional groups and hydroxyl groups on fiber molecules are subjected to esterification reaction to be firmly bonded on the surfaces of the fibers; the hydrophobic long-chain fatty group turns to the paper surface, so that the hydrophobic effect is obtained, the stability and the sizing effect of the AKD surface sizing agent are remarkably improved by adding the AKD special cationic polymer emulsifier, meanwhile, the hydrolysis and migration tendency of AKD is limited, and AKD latex is well protected.

A process for the separation of a protonated organic hydroxylamine compound and an organic nitrosonium compound from each other under acidic conditions, wherein a mixture of protonated organic hydroxylamine compound and organic nitrosonium compound is brought in contact with a hydrophobic resin to retain the organic hydroxylamine compound on the hydrophobic resin. A process for the oxidation of a hydroxy compound in the presence of an organic nitroxy compound and optionally a primary oxidant, using this separation process is also disclosed.

A reactive compound represented by the following formula (I):

[In the formula (I), Z represents a divalent group. A plurality of Y may be the same or different, and represent a monovalent boronate residue having at least one hydroxyl group, Ar¹ and Ar² may be the same or different, and represent a trivalent aromatic hydrocarbon group or a trivalent heterocyclic group.].

The invention discloses a preparation method of a mixed-mode liquid chromatography filler based on a single selector. The method comprises the following steps: firstly obtaining silane with amide/amine multiple polar groups through a selective amidation technology, then immobilizing the silane on silica gel, and finally masking residual silicon hydroxyl by using a conventional alkaline small-molecular end-capping agent to prepare a class of novel high performance liquid chromatography stationary phases. According to the method disclosed by the invention, the adopted selective amidation has reaction specificity, the preparation process adopts a one-pot multi-step reaction method, the use amount of a solvent is reduced, the surface chemical property of the obtained filler is homogeneous, the filler has remarkable alkalinity and excellent hydrophilicity, and the problems that the conventional mixed mode filler is non-homogeneous and is disordered in application, and the defects that a conventional mixed mode filler is heterogeneous, mixed and disordered during application, and unstable in batch repeatability and chromatographic reproducibility of the filler are overcome.

The invention discloses a method for preparing obeticholic acid intermediate and obeticholic acid thereby, wherein the obeticholic acid intermediate is prepared with 3A-hydroxy-6-vinyl-7-oxo-cholanicacid as a raw material through carbonyl reduction and hydroxyl protection. The obeticholic acid intermediate has two benzene ring structures and has strong ultraviolet absorption, so that quality researching can be carried out by means of an ultraviolet detector, thus guaranteeing mass controllability of the raw material in the last one step. At room temperature, the intermediate is a solid, and can be purified through regular purification methods such as recrystallization. Then through Pt/C catalyst for reduction, the obeticholic acid is obtained. In the aspect of reaction process, firstly, the reduction of the olefinic bond is completed in the Pt/C catalytic reduction, so that the reaction is convenient to trace. The method is high in reaction yield and is complete in conversion, so thatpurification difficult of the finish product is reduced.

The invention relates to a preparation method of hydroxyl polyurethane (PHU). An isocyanate route for synthesizing traditional polyurethane (PU) is adopted in the method to synthesize PHU for the first time, and the preparation of linear PHU is divided into two steps, namely prepolymerization and chain extension. The preparation method comprises the following steps: firstly, reacting excessive diisocyanate monomers with macromolecular diol to obtain an isocyanate-terminated prepolymer; then adding a ketal (aldehyde) protected diol chain extender for a reaction with the prepolymer to obtain PU-ketal (aldehyde); and finally, hydrolyzing a ketal (aldehyde) protecting group in a PU-ketal (aldehyde) structure into a hydroxyl group under an acidic condition to obtain PHU. The preparation of cross-linked PHU comprises the following steps: subjecting the linear PHU to reacting with a diisocyanate monomer, and controlling a ratio of the PHU to the diisocyanate monomer to allow a part of hydroxyl groups to be still reserved on a PHU main chain, thereby obtaining the cross-linked PHU. Compared with the prior art, the method has the advantages of simple operation, easily available raw materials, low economic cost and high product yield, and is suitable for large-scale industrial production.

The invention discloses a synthesis method of a micafungin side chain intermediate. An important side chain intermediate for synthesizing micafungin can be obtained through only three steps, and the steps are simple. Firstly, 4-pentoxyl acetophenone and methyl p-formylbenzoate as initial raw materials are subjected to an aldol condensation reaction under the action of an alkali catalyst cesium carbonate to obtain an intermediate M1; then, the intermediate M1 and N-hydroxyl p-toluenesulfonamide are cyclized under the action of the alkali catalyst cesium carbonate to obtain an intermediate M2; and finally, transesterification reaction is carried out on the intermediate M2 and 1-hydroxybenzotriazole to obtain the high-purity micafungin side chain intermediate shown in the formula M (See the specification). A brand-new synthesis route is provided, and a foundation is laid for preparation of a final product micafungin.

The invention belongs to the technical field of compound preparation. The invention relates to a preparation method of phosphatidylglycerol monosodium salt, in particular to a preparation method of phosphatidylglycerol monosodium salt containing two different side chains. The preparation method comprises the following steps: taking D-mannitol as an initial raw material, heating D-mannitol in acetone to generate 1,1,5,6-isopropylidene-D-mannitol; carrying out sodium periodate oxidation and sodium borohydride reduction to obtain iso-propylidene glycerol; carrying out condensation reaction with fatty acid containing an R1 element, then removing acetal protective groups in the presence of acid; selectively protecting primary hydroxyl by using a silane protective agent, reacting secondary hydroxyl with another fatty acid containing a R2 element, removing silane protection, reacting the de-protected product with phosphorus oxychloride and iso-propylidene glycerol, removing acetal protectivegroups by using an acid, and finally carrying out a sodium salt treatment to obtain a final product. The synthesis of phosphatidyl monosodium salt containing two different side chains can be realized,and the production process is simple, environment-friendly and easy to operate.

The invention relates to a synthesis method of 2-chloro-1-(2, 2-dimethyl-4H-benzo [1, 3] dioxin-6-yl) ethanone, the method comprises the following steps: (1) carrying out hydroxymethylation on methyl 4-hydroxybenzoate to obtain methyl 4-hydroxy-3-(hydroxymethyl) benzoate; (2) carrying out acetonylidene protection on ortho-dihydroxyl of the 4-hydroxy-3-(hydroxymethyl) methyl benzoate, so as to obtain 2, 2-dimethyl-4H-benzo [d] [1, 3] dioxin-6-carboxylic acid methyl ester; and (3) carrying out chloromethylation on the 2, 2-dimethyl-4H-benzo [d] [1, 3] dioxin-6-carboxylic acid methyl ester, so as to obtain the 2-chloro-1-(2, 2-dimethyl-4H-benzo [d] [1, 3] dioxin-6-yl) ethanone. The synthesis route does not involve a Friedel-Crafts acylation reaction, liquid bromine does not need to be used, the initial raw materials belong to bulk chemicals, the synthesis route is short, the synthesis route is safer and more environmentally friendly, and mass production of the 2-chloro-1-(2, 2-dimethyl-4H-benzo [1, 3] dioxin-6-yl) ethanone is easy to achieve.

The invention relates to a proton exchange membrane and a preparation method thereof. The proton exchange membrane is prepared from the following raw materials: proton exchange resin, isocyanate, unsaturated ester and a photoinitiator, wherein the proton exchange resin contains hydroxyl; the unsaturated ester contains hydroxyl; the isocyanate at least contains two isocyanate groups; and carrying out photocuring membrane formation on the reaction product of the proton exchange resin, isocyanate and unsaturated ester to obtain the proton exchange membrane. Unsaturated ester is grafted on proton exchange resin through isocyanate, so that a photocurable group (unsaturated double bond) is introduced into the proton exchange resin, a photoinitiator is introduced into the preparation raw materials of the proton exchange membrane, and the proton exchange membrane can be formed by illumination in the presence of a photochemical source and the photoinitiator. The illumination membrane forming process of the proton exchange membrane does not need high temperature, the problem that a large amount of energy is consumed in the traditional thermocuring process can be solved, and the requirement for environmental protection is met.

The invention discloses a side chain type amino silicone oil emulsion and a preparation method thereof, and the preparation method comprises the following steps: under the protection of inert gas, carrying out reduced pressure reaction on linear hydroxyl silicone oil and an amino-alkyl coupling agent under the catalysis of TMAH, and then carrying out heating treatment under the reduced pressure condition to obtain side chain type amino silicone oil; the preparation method comprises the following steps: emulsifying side chain type amino silicon oil to obtain the side chain type amino silicon oil emulsion; according to the preparation method disclosed by the invention, through a specific preparation process and a specific emulsification method, the prepared side chain type amino silicone oil emulsion has excellent transmittance and stability, the transmittance of the side chain type amino silicone oil emulsion can be up to 97%, and meanwhile, the side chain type amino silicone oil emulsion has excellent stability.

The invention discloses a metal spray cleaning agent which is composed of the following components including, by weight, 8% of sodium metabisulfite, 2% of ferrous sulfate, 3% of sodium tripolyphosphate, 2% of 3-methoxyl-3-methyl-butanol, 15% of an aluminum corrosion inhibitor, 10% of polyethylene glycol, 2% of cold-drawn polypropylene fiber, 2% of a silane coupling agent, 10% of polypropylene, 2%of a defoamer, 5% of diisocyanate, 4% of phosphorus-containing polyol, 5% of aluminum chloride, 2% of sodium nitrate, 1% of anhydrous borax, 1% of 2-hydroxyl-2-methyl-1-acetone, 5% of hexamethyl disilazane, 1% of polytetrafluoroethylene and the balance water. The cleaning agent can still maintain a low-foam or even non-foaming state when deburring is carried out at a spray pressure of 20 MPa to 15MPa at 20-40 DEG C, and the residual degree after cleaning is low.

The invention discloses a polymer modified carbon nanotube and a preparation method thereof. The preparation method of the carbon nanotube comprises the following steps: (1) in an aprotic organic solvent, reacting a hydroxylated carbon nanotube with an alkali metal compound or an alkali metal complex to obtain a carbon nanotube alkoxide; and (2) initiating a vinyl-containing monomer to polymerizeby using the carbon nanotube alkoxide to obtain the vinyl polymer modified carbon nanotube. The method has the advantages of simple preparation, mild reaction, safe operation and the like.

The invention discloses a bio-based concrete workability regulator and a preparation method thereof. The bio-based concrete workability regulator comprises the following components in parts by weight: 30-50% of glycerol, 20-40% of a lignin derivative, 10-15% of reducing sugar, 1-3% of water-soluble polyvinyl alcohol, 1-5% of unsaturated anhydride, 0.5-1.5% of polyisocyanate, 1-4% of unsaturated carboxylic acid, 2-6% of an unsaturated sulfonic acid derivative and 0.8-3% of an initiator. According to the invention, bio-based macromolecules are adopted as raw materials, the use ratio of chemical raw materials is reduced, a plurality of action sites and cross-linked structures are formed by using a polyhydroxy structure and polyfunctionality of natural polymer derivatives, the coating capacity of slurry to aggregate is improved, concrete coating is improved, the segregation and bleeding phenomena of concrete can be effectively improved, the concrete flowability is not influenced, obvious air entraining and retarding side effects are avoided, and the acting effect is lasting and stable.