3 results about "Polyamino acid" patented technology

The invention relates to a 3D printing modified polyamino acid material. Raw materials for preparing the 3D printing modified polyamino acid material comprise, by weight, 75-85 parts of polyamino acid, 1-5 parts of a chain extender, 1-5 parts of a crosslinking agent, 0.5-1 part of a nucleating agent, 5-10 parts of a toughening agent, 0.1-0.5 parts of a thermal stabilizer, 1-5 parts of a reinforcing agent and 0.3-0.8 parts of an antioxidant. A low temperature crushing mixing reaction technology is used to modify polyamino acid, so the toughness, the impact strength and the thermal deformation temperature of the modified polyamino acid are greatly improved, thereby the polyamino acid material has a good application prospect in 3D printing.

The invention provides a polyethylene glycol-polyamide-amine-polyamino acid linear-dendritic block polymer with a structure shown as a formula I, II, III or IV. The polyethylene glycol in the block polymer can be used for improving the biocompatibility of the block polymer and prolonging the circulation time of the block polymer in the blood, and a polyamino acid block can be used for ensuring the favorable degradation performance of a product and can be discharged in vitro after being degraded in vivo. The block polymer provided by the invention is simple in preparation method and safe and nontoxic in product. The block polymer is used as a carrier and assembled in water to form nanoparticles, and a model drug adriamycin is carried, so that drug-carried nanoparticles are obtained, and the drug-carried nanoparticles have a certain controlled-release function and can be used for effectively inhibiting the proliferation of cancer cells in cell experiments. Therefore, the block polymer has the potential application as a nano-drug carrier.