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4 results about "Proline" patented technology

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated NH₂⁺ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO⁻ form under biological conditions), and a side chain pyrrolidine, classifying it as a nonpolar (at physiological pH), aliphatic amino acid. It is non-essential in humans, meaning the body can synthesize it from the non-essential amino acid L-glutamate. It is encoded by all the codons starting CC (CCU, CCC, CCA, and CCG).

SPECT imaging agent for FAP-alpha specific tumor diagnosis

ActiveCN111991570AStable coordinationExcellent Tumor Imaging CapabilitiesRadioactive preparation carriersTPPTSImaging agent
The invention relates to an SPECT imaging agent for FAP-alpha specific tumor diagnosis. The imaging agent is formed by taking a micromolecular FAP-alpha inhibitor of a modified N-4-quinolyl-glycine-(2S)-cyanoproline skeleton as a precursor compound, taking 99mTc as radionuclide and taking N-tris (hydroxymethyl) methylglycine (Tricine) and triphenylphosphine tri-m-sodium sulfonate (TPPTS) as synergistic ligands. Compared with the prior art, the imaging agent has high sensitivity, more excellent in-vivo biological distribution is shown, compared with the prior art, the complex has the advantagesof higher tumor uptake and tumor / organ uptake ratio, more stable coordination property, and excellent in-vivo and in-vitro stability. Due to the obvious coordination structure characteristics of theimaging agent, a one-step marking kit technology can be used, and the imaging agent has better druggability and is suitable for industrial production and clinical popularization.
Owner:JIAXING PHARBERS GENESIS PHARMACEUTICAL TECHNOLOGY CO LTD

Foliar fertilizer for improving crisp pear quality and application method thereof

InactiveCN109053258AIncrease the sugar contentHigh in vitaminsNitrogenous fertilisersFertilizer mixturesArginineManganese
The invention discloses foliar fertilizer for improving crisp pear quality and an application method thereof. The pear foliar fertilizer is prepared from arginine, proline, lysine, glycine, glutamic acid, leucine, zinc, manganese, copper, iron, threonine, asparaginic acid, alanine and phenylalanine, wherein arginine and proline have a promoting effect on pear growth development; lysine, glycine, glutamic acid, leucine, the zinc, the manganese, the copper and the iron have a promoting effect on pear photosynthesis; threonine, asparaginic acid, alanine and phenylalanine have a promoting effect on pear stress resistance. The application method of the pear foliar fertilizer comprises the steps: mixing with water to dilute the pear foliar fertilizer spraying 2 to 4 times in a fruit expanding period, spraying to the front and back sides of leaves when no wind, no rain and no burning sun and spraying until the leaves are wet in each spraying. When the fertilizer disclosed by the invention isused, pear photosynthesis and metabolism are promoted, the sugar content and the vitamin content of crisp pears are better improved, and pear quality is improved.
Owner:HEFEI LVNONG FERTILIZER IND +1
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