3 results about "Stratum corneum" patented technology

The invention discloses a facial mask added with peony extract and a preparation method thereof. The facial mask is prepared from the following raw materials: peony extract, nicotinamide, inositol, oil-soluble vitamin E, an emulsifier, chrysanthellum indicum, honeysuckle flower, pseudo-ginseng root, eucommia bark, glycerin, low-molecular hyaluronic acid, an antibacterial agent and deionized water. According to the invention, substances like a peony flower stock solution, peony seed oil, chrysanthellum indicum, inositol, low-molecular hyaluronic acid, honeysuckle flower and pseudo-ginseng root are mixed to form a compound, so the whitening and skin-tendering facial mask suitable for modern women is formed; and the facial mask can effectively improve the antioxidant capacity of skin, injects sufficient moisture into skin, prevents moisture in the stratum corneum of skin from evaporating, enables loaded plant essence to be easily absorbed, maintains the face to be moist, has good whitening and repairing effects, can effectively remove free radicals in skin, prevents accelerated aging of facial skin, reduces facial wrinkles and has ideal antioxidation and skin aging delaying effects.

The invention relates to a microneedle for treating leucoderma as well as a preparation method and application thereof, and relates to the field of medical biological materials. The microneedle comprises hydrogel, a water-soluble substrate material and an active pharmaceutical ingredient, the active pharmaceutical ingredient is selected from at least one of the following raw materials: melanotropin, tofacitinib, tacrolimus, pimerolimus or ruxolitinib. According to the microneedle, hydrogel with high mechanical strength is adopted, the microneedle can pierce the cuticle, the hydrogel is insoluble in water, the prepared microneedle does not need a large amount of organic solvent, after the microneedle pierces the cuticle, the medicine for treating leucoderma is directly delivered to the epidermal layer and the corium layer through the diffusion effect, and the medicine application effect is enhanced; meanwhile, the substrate of the microneedle is made of a water-soluble substrate material, after the skin is punctured by the microneedle, water is absorbed, the tip of the microneedle and the substrate of the microneedle are automatically separated, and the tip which is insoluble in water is remained in the skin, so that active pharmaceutical ingredients attached to the microneedle are released in a long-acting manner, and the administration frequency is reduced.