Vagina mold containing estriol

一种雌三醇、模具的技术，应用在含有雌三醇的阴道模具领域，能够解决降低人造阴道挛缩率等问题，达到降低挛缩率的效果

Inactive Publication Date: 2013-11-20
SUZHOU MARTAI NEW MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there is no report about a vaginal mold that can greatly reduce the contracture rate of the artificial vagina and release estrogen

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] 1. Drugs and preparations:

[0016] 1. Estrogen: raw material drug of estriol.

[0017] 2. Silicone rubber compound: purchased from Shanghai Rubber Products Research Institute. The silicone rubber used in the present invention is a two-component room temperature vulcanized silicone rubber. Before vulcanization, there are two components, A and B. Among them, the A component contains a catalyst, and the B component contains a crosslinking agent. They do not react with each other, and after blending with each other, the polymerization reaction can be carried out because the catalyst and the crosslinking agent are mixed together.

[0018] Second, equipment

[0019] Pressure forming machine (model: XLB-D400-400), rubber mixing machine (model: JTC-752A), electronic platform scale (model: TSC-6), electric blast drying oven (model: 101A-1B), drying oven ( Model: 101-3), three-roll mill (model: SG-150), weighing display (model: XK3130).

[0020] Three, material preparation ...

Embodiment 2

[0026] One, medicine and preparation: Same as Example 1.

[0027] Two, equipment: with embodiment 1.

[0028] 3. Material preparation: Weigh 100 g of silicone rubber material, 30 g of estriol, and the others are the same as in Example 1.

[0029] 4. Vaginal mold preparation: Same as Example 1.

Embodiment 3

[0031] One, medicine and preparation: Same as Example 1.

[0032] Two, equipment: with embodiment 1.

[0033] 3. Material preparation: Weigh 100 g of silicone rubber material, 50 g of estriol, and the others are the same as in Example 1.

[0034] 4. Vaginal mold preparation: Same as Example 1.

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PUM

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Abstract

The invention relates to a vagina mold containing estriol. The vagina mold is composed of silicone rubber and the estriol, wherein the weight ratio of the silicone rubber and the estriol is 20: (5-8). The vagina mold containing the estriol has the advantages that the vagina mold containing estrogen greatly lowers the contracture rate of a man-made vagina. The silicone rubber and the estrogen are combined to manufacture the vagina mold with the estrogen slow releasing ability, and therefore vagina mold treatment and estrogen treatment are effectively combined, and the vagina mold with the slow releasing function has great potential in future clinical application.

Description

technical field [0001] The invention relates to a vaginal mold, in particular to a vaginal mold containing estriol. Background technique [0002] Most patients with congenital absence of vagina have Rokitansky-Kuster-Hauser syndrome (RKH syndrome), which is the result of bilateral paramesonephric duct hypoplasia during the embryonic period, and the karyotype is 46XX. The treatment of patients with congenital absence of vagina has surgical treatment and non-surgical treatment. Surgical treatment includes vulvovaginoplasty (Williams method), acupoint skin grafting method (McIndol method), peritoneal vagina replacement method (Rothman method), sigmoid colon replacement vagina method (Pratl method), amniotic membrane replacement vagina method, and new biomaterial vaginal reconstruction, etc. , The application of the vaginal mold is a very important part of the post-vaginoplasty treatment. A vaginal mold should be placed for 3 months to half a year after the operation to preven...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/82A61M31/00A61K9/02A61K31/565A61P15/02
Inventor 王强
Owner SUZHOU MARTAI NEW MATERIAL CO LTD
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