Preparation method of cordyceps sinensis oral liquid and specified culture medium

一种口服液、培养基的技术,应用在虫草口服液的制备领域,能够解决活性物质少、冬虫夏草成分低、营养不全面等问题,达到有效成分含量高、缩短生产周期、微量元素多的效果

Inactive Publication Date: 2016-11-16
宫晶晶
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Cordyceps sinensis can not be cultivated artificially
At present, most of the domestic health care products or pharmaceutical industries use Cordyceps militaris or fermented mycelium instead of Cordyceps sinensis, while the traditional fermentation method mainly uses chemical element culture medium, which is not comprehensive and single in nutrition, and the main components of Cordyceps sinensis are low and active substances are few, greatly Affect and reduce the quality and function of the product

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] 1. Shaker bottle formula: The percentage of raw materials by weight is: bran 0.5%, corn 2.5%, soybean 2.5%, oat 0.5%, sugar 2.5% (among them, sugar is glucose and sucrose, each accounting for 50%), yeast Powder 1%, bee pollen 0.2%, potassium dihydrogen phosphate 0.2%, the balance is water, and the pH value is 5.5.

[0024] 2. Method: directly boil the bran and filter the juice, soak the corn, soybeans and oats without hard core, beat and filter to remove the slag, add other auxiliary materials to the filtered juice at one time, make up water in proportion, put it into the Erlenmeyer flask, the liquid volume is 30 % or so, put a cotton plug (made by wrapping cotton with gauze) or a silicone plug into the mouth of the bottle, wrap it in kraft paper and sterilize it under high pressure, drain the cold air and heat up to 121°C, time it for 35 minutes, wait for the hands When returning to zero, open the exhaust valve and open the lid. When the temperature of the culture med...

Embodiment 2

[0031] 1. Shaker bottle formula: The percentage of raw materials by weight is: bran 1.0%, corn 1.5%, soybean 2%, oat 1.5%, sugar 1.5% (among them, sugar is glucose and brown sugar, each accounting for 50%), yeast Powder 2%, bee pollen 0.1%, potassium dihydrogen phosphate 0.2%, the balance is water, and the pH value is 6.5.

[0032] 2. Method: directly boil the bran and filter the juice, soak the corn, soybeans and oats without hard core, beat and filter to remove the slag, add other auxiliary materials to the filtered juice at one time, make up water in proportion, put it into the Erlenmeyer flask, the liquid volume is 30 % or so, put a cotton plug (made by wrapping cotton with gauze) or a silicone plug into the mouth of the bottle, wrap it in kraft paper and sterilize it under high pressure, drain the cold air and raise the temperature to 123°C, time it for 35 minutes, wait for the needle When returning to zero, open the exhaust valve and open the lid. When the temperature o...

Embodiment 3

[0039] 1. Shaker bottle formula: The percentage of raw materials by weight is: bran 1.5%, corn 2.5%, soybean 1.5%, oat 1.5%, sugar 2.5% (among them, sugar is glucose and white sugar, each accounting for 50%), yeast Powder 1%, bee pollen 0.2%, potassium dihydrogen phosphate 0.2%, the balance is water, and the pH value is 7.

[0040] 2. Method: directly boil the bran and filter the juice, soak the corn, soybeans and oats without hard core, beat and filter to remove the slag, add other auxiliary materials to the filtered juice at one time, make up water in proportion, put it into the Erlenmeyer flask, the liquid volume is 30 % or so, put a cotton plug (made by wrapping cotton with gauze) or a silicone plug into the mouth of the bottle, wrap it in kraft paper and sterilize it under high pressure, drain the cold air and heat up to 121°C, time it for 35 minutes, wait for the hands When returning to zero, open the exhaust valve and open the lid. When the temperature of the culture m...

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PUM

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Abstract

The invention discloses a preparation method of cordyceps sinensis oral liquid and a specified culture medium. The present situation that a bio-fermentation technology is used for filling up the gap of wild cordyceps sinensis is relieved fundamentally, and the content of the main ingredients of cordyceps sinensis in the oral liquid is increased. The culture medium mainly adopts natural plants and is natural, green, free of chemical residues and comprehensive in nutrition, and more microelements are contained; glucose and one of sucrose, white sugar and brown sugar are added together, and the ingredients are comprehensive and lasting; vegetable oil is used for replacing a traditional chemical defoamer and is nutritious and free of chemical residues; in the production and processing and filling process of the oral liquid, traditional or modern physical or chemical methods such as high temperature, drying, extraction and crushing are not adopted in the whole process, all the active ingredients in the oral liquid are effectively reserved, and the active ingredients are not damaged or destroyed; additives such as a preservative, a thickener, a stabilizer and a colorant are not added from the step of preparing shake flasks to the step of filling the product, and the content of the effective ingredients of the oral liquid is high.

Description

technical field [0001] The invention relates to a preparation method of oral liquid, in particular to a preparation method of Cordyceps oral liquid. Background technique [0002] Cordyceps sinensis is a precious Chinese medicinal material in my country, which belongs to medicinal fungi. Wild Cordyceps sinensis is mainly distributed in the high-altitude areas of the Qinghai-Tibet Plateau in my country. [0003] In recent decades, the output of Cordyceps sinensis has declined in recent years, and the price has increased year by year. Cordyceps sinensis cannot be artificially cultivated at present. At present, most of the domestic health care products or pharmaceutical industries use Cordyceps militaris or fermented mycelium instead of Cordyceps sinensis, while the traditional fermentation method mainly uses chemical element culture medium, which is not comprehensive and single in nutrition, and the main components of Cordyceps sinensis are low and active substances are few, g...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/14A61K36/068A61K9/08A23L2/38A23L33/00C12R1/645A23L11/50A23L11/65
CPCA23L2/382A61K9/0053A61K9/08A61K36/068C12N1/14A23V2002/00A61K2236/19A23V2200/30
Inventor 宫晶晶
Owner 宫晶晶
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