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6 results about "Synergy" patented technology

Synergy is the creation of a whole that is greater than the simple sum of its parts. The term synergy comes from the Attic Greek word συνεργία synergia from synergos, συνεργός, meaning "working together".

PH-responsive polyethylene glycol-anticarcinogen conjugate, and synthetic method and application thereof

InactiveCN102475891APassive targetingBiocompatibleKetone active ingredientsPharmaceutical non-active ingredientsAnticarcinogenNano size
The invention discloses a pH-responsive polyethylene glycol-anticarcinogen conjugate, and a synthetic method and application thereof. After anticarcinogen molecules and polyethylene glycol are covalently linked through pH-sensitive phenylimide linkage, the conjugate is formed, wherein, anticarcinogen can be doxorubicin, epirubicin, daunorubicin, demethoxydaunorubicin or hydrochlorides of the above-mentioned anticarcinogens. The phenylimide linkage is stable under the condition of a normal physiological pH value but undergoes hydrolysis under the condition of a slightly acidic pH value, e.g., a solid tumor cell external pH value and a cell endosome and lysosome pH value; that is, the phenylimide linkage is sensitive to changes of pH values in a range of 7.4 to 4.5 or to below 4.5. The polyethylene glycol-anticarcinogen conjugate has amphiphilic nature and can form nanometer-scale micelle in a saline solution through self-assembly; the micelle can be used as a drug carrier to carry hydrophobic drugs and form a nanometer micelle preparation cladded with drugs, thereby realizing synergy therapy of a plurality of drugs.
Owner:INST OF CHEM CHINESE ACAD OF SCI

Application of amomum tsao-ko essential oil

InactiveCN110123982AEasy to see throughFunction increaseNervous disorderEssential-oils/perfumesDiseaseSide effect
The invention discloses an application of amomum tsao-ko essential oil, an application of the amomum tsao-ko essential oil in preparing drugs for the treatment or prevention of brain dysfunction and other disorder disease and an application of the amomum tsao-ko essential oil in preparing health products for improving brain function and disorder diseases. For the first time, the amomum tsao-ko essential oil is found to have a new use in medicine or large health products that show activity in brain function and disorder diseases of experimental animals, and for the first time, the amommum tsao-ko essential oil or arbitrary components containing the amommum tsao-ko essential oil can improve brain function such as Alzheimer's disease, depression and anxiety in animal body models and the symptoms of disordered animals; compared with traditional medicine for treating the brain function and disorders, the amomum tsao-ko essential oil or the arbitrary components thereof has the mechanism of inhibiting the action of multi-molecular synergy of the cholinesterase and regulating the synergistic action of multiple molecules, such as neurotransmitters, on multiple targets, and is good in drug substitution and easy to penetrate the blood-brain barrier, and the advantages of toxicological safety, stable metabolism, long half-life period and small side effects are achieved.
Owner:KUNMING UNIV OF SCI & TECH
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