6 results about "Thiazole" patented technology

The invention provides thiazole heterocyclic compounds, and a preparation method and application thereof. The thiazole heterocyclic compounds have a general structural formula as described in the specification. Results of cell-level experiments show that the thiazole heterocyclic compounds provided by the invention can inhibit proliferation of K562, HL60 and KGla cells. In particular, the compound (compound 4c) in an embodiment 3 can also inhibit proliferation of K562, HL60 and KGla cells under the condition that the concentration of the compound is lower than the concentration of a positive control drug dasatinib. Thus, the thiazole heterocyclic compounds provided by the invention can be used for treating leukemia.

The invention discloses a quick-drying stable antirust oil. The quick-drying stable antirust oil is prepared from the following raw materials by weight: 63 to 70 parts of base oil SN150, 2 to 4 parts of terpene resin, 1 to 2 parts of triallyl cyanurate, 0.7 to 2 parts of 2-mercaptobenzothiazole, 0.2 to 0.5 part of sodium carbonate, 1 to 2 parts of isobutanol, 0.4 to 1 part of magnesium naphthenate, 5 to 7 parts of lanolin, 1 to 2 parts of lauric diethanolamide, 1 to 2 parts of 1,2-epoxybutane and 5 to 6 parts of an antirust aid. The antirust oil provided by the invention has actual drying time of 0.5 to 2 h; an antirust film is bright and transparent and hardly undergoes color changing and oxidation; a coating of the antirust oil is stable, has high salt fog resistance, resistance to dampness and heat, aging resistance and the like and exerts a good protection effect on a substrate.

The invention belongs to the technical field of lubricants, and relates to a functional rolling liquid of water-based nano Cu and a preparation method of the functional rolling liquid. The functional rolling liquid is used for lubricating a rolled copper foil in a rough rolling process. The preparation method comprises the following steps: by taking nano Cu with good anti-corrosion and anti-rusting performance as an extreme pressure agent and taking methylbenzene, polyethylene glycol and sodium dodecyl benzene sulfonate as a dispersing agent, sequentially adding deionized water, the sodium dodecyl benzene sulfonate, the methylbenzene, the polyethylene glycol, triethanolamine, oleic acid, aniline and mercapto-1,3,4-thiazole and putting into a reaction kettle at a revolving speed of 80 to 120 revolutions per minute, heating and stirring, adding the nano Cu when a temperature reaches 70 DEG C to 80 DEG C, carrying out heat preservation and further stirring for 45 to 60 minutes, then stopping the heating and further stirring until reaching a room temperature so as to obtain a turbid suspension liquid in red brown, namely, a required water-based rolling liquid. As the water-based rolling liquid is used, the pollution caused by the traditional cold-rolling emulsified oil is reduced, and the slow-release anti-rusting performance of a rolled copper plate/strip can be obviously improved. Thus, the rolled copper plate/strip is good in surface quality and long in anti-corrosion period.

The invention relates to a ketonic oxime type silicone sealant and a preparation method thereof. The ketonic oxime type silicone sealant comprises the following raw material components in parts by weight: 100 parts of dyhydroxy polysiloxane, 40-80 parts of dimethyl silicon oil, 0.5-2 parts of a component A, 0.5-2 parts of a component B, 15-25 parts of packing, 5-12 parts of a cross-linking agent,0.5-3 parts of a silane coupling agent and 0.05-0.5 part of a catalyst, wherein the component A comprises nanosilver supported by a carrier; the component B comprises a thiazole compound. The ketonicoxime type silicone sealant is not liable to yellowing, good in anti-mold effect, short in surface dry and curing time and convenient to construct.

The invention provides a green method for converting a thiazolidine derivative into a carbonyl compound, and belongs to the field of green organic synthetic chemistry. According to the method, a co-catalysis system is formed by H2O2-CeBr3 under neutral, open and room-temperature conditions, hypobromous acid is generated in situ by H2O2-CeBr3 to serve as a direct oxidizing agent, and the tetrahydrothiazole derivative is oxidized into the corresponding carbonyl compound within a short time. The used reagents H2O2 and CeBr3 and the solvent acetonitrile are cheap and easy to obtain, the reaction is mild and efficient, the product yield is high, the tolerance of functional groups is good, the operation is simple and convenient, the method is environment-friendly, the application of the tetrahydrothiazole protecting groups in organic synthesis is effectively expanded, and the method has a good application prospect.

The invention belongs to the technical field of optical adhesives, and particularly relates to a hot-melt optical adhesive with an ultraviolet blocking function and a preparation method thereof, and the hot-melt optical adhesive comprises the following components in parts by weight: 100 parts of a mixed copolymer; 1-5 parts of a coupling agent; 0.2-0.6 part of an antioxidant; 0.1-0.6 part of a light stabilizer; 5-10 parts of a water blocking agent; the mixed copolymer is obtained by reacting an ethylene-vinyl acetate copolymer, a cross-linking agent, an anti-ultraviolet agent, an initiator and a polymerization initiator in a weight part ratio of 100: (5-10): (0.5-1): (1-3): (0.5-1); the anti-ultraviolet agent is composed of 4-methacrylamido salicylic acid and thiazolyl-2 (1H)-pyridone-4-methallyl formate, and the thiazolyl-2 (1H)-pyridone-4-methallyl formate is obtained in the mode that citric acid and 2-aminoethanethiol are subjected to a reaction to obtain an intermediate product, and then the intermediate product is subjected to methallyl alcohol esterification to obtain the thiazolyl-2 (1H)-pyridone-4-methallyl formate. According to the optical adhesive, the optical adhesive has a shielding effect on ultraviolet rays with the wavelength of 320-400 nm in sunlight, so that the damage of most ultraviolet rays to the optical cement is reduced, and the service life of the optical cement is prolonged.