In various embodiments, the present disclosure pertains to a composition composed of chlophedianol and menthol, or method of use thereof, having a form of a chewable composition, a chewable gummy, a chewable tablet, a chewable candy, a soft chewable, a hard chewable, a tablet, a capsule, a quick dissolving tablet or capsule, a lozenge, an orally disintegrating tablet, and a liquid composition. In some embodiments, the composition is formulated to alleviate respiratory tract infection symptoms, symptoms cause by allergies, symptoms cause by the common cold, symptoms cause by acute bronchitis, symptoms cause by pneumonia, symptoms cause by pertussis, symptoms cause by influenza, symptoms cause by tuberculosis, post-infectious cough symptoms, dry cough symptoms, productive cough symptoms, non-productive cough symptoms, or coughing and coughing-related symptoms selected from the group consisting of throat soreness, muscle strains or soreness in the abdomen or throat, throat irritation, and lung irritation, or combinations thereof.