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5 results about "Ethyl cellulose" patented technology

Ethyl cellulose (or ethylcellulose) is a derivative of cellulose in which some of the hydroxyl groups on the repeating glucose units are converted into ethyl ether groups. The number of ethyl groups can vary depending on the manufacturer.

Aspirin sustained-release tablets and preparation method thereof

InactiveCN111700869AOrganic active ingredientsPharmaceutical non-active ingredientsEthyl celluloseExtended release tablets
The invention relates to aspirin sustained-release tablets and a preparation method thereof. The sustained-release tablets include main drug-aspirin and ingredients; the ingredients include starch, polyacrylic resin II, hydroxypropyl methylcellulose, ethyl cellulose and a 3% hydroxypropyl methylcellulose alcoholic solution; and the starch, the polyacrylic resin II, the hydroxypropyl methylcellulose and the ethyl cellulose in the ingredients are smashed and sieved through a sieve with 80 meshes for later use. The preparation method of the 3% hydroxypropyl methylcellulose alcoholic solution in the ingredients includes taking 135 parts of tartaric acid to add to 360 parts of purified water, performing heating to about 70 DEG C to stir to complete dissolution, then adding 36 parts of polysorbate 80, and performing stirring to complete dissolution so as to obtain a solution A; taking 54 parts of the hydroxypropyl methylcellulose, while adding, performing stirring to uniformly dispersing thehydroxypropyl methylcellulose in 1152 parts of ethanol, and obtaining a solution B; and uniformly mixing the solutions A and B, and performing standing for 8-72 h at 18-26 DEG C. The sustained-release tablets have the advantages of being sustainably stable in release rate, free from pollution and almost insoluble in stomach.
Owner:郑州市协和制药厂
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