Biological composite material, preparation method thereof and biological scaffold

[0032] On the other hand, on the basis of the biocomposite material described above, the embodiment of the present invention also provides a preparation method of the biocomposite material. The preparation method technology of the embodiment of the present invention biocomposite material is as figure 1 As shown, it includes the following steps:

[0033] Step S01. Mixing the lithium source that provides lithium ions with the components contained in the biocompatible material and the solvent to prepare a slurry;

[0034] Step S02. Drying the slurry.

[0035] Specifically, the type of the lithium source and the components contained in the biocompatible material in the step S01 are as described above in the biocomposite material, and will not be repeated here to save space. The solvent can be a commonly used solvent for preparing the biocompatible material, such as in one embodiment, the solvent includes 1,4-dioxane, water, ethanol, methanol, dimethyl sulfoxide, acetone , At least

[0045] This embodiment provides a biocomposite material and a preparation method thereof. The biocomposite material includes polylactic acid-glycolic acid copolymer (PLGA), β calcium phosphate (TCP) and lithium chloride, wherein the mass ratio of PLGA, TCP and lithium chloride is 4.368:1.092:0.273. And PLGA (polylactic acid-glycolic acid copolymer) was purchased from Shandong Medical Device Research Institute, PLGA molecular weight is 100,000, and the molar ratio of lactic acid and glycolic acid is 70:30; TCP is purchased from Beijing Modern Oriental Fine Chemical Co., Ltd. ; Lithium chloride was purchased from Sigma, with a purity greater than 99%; and the rapid prototyping machine for biological materials was developed by the Department of Mechanical Engineering, Tsinghua University, model CLRF-2000-II.

[0046] The preparation method of the biocomposite material comprises the following steps:

[0047] S11: Put 092g TCP in a 15ml centrifuge tube, add 10ml 1,4-dioxane (C 4 h

[0052] This embodiment provides a biocomposite material and a preparation method thereof. The biocomposite material includes lactic acid-glycolic acid copolymer (PLGA) and lithium chloride, wherein the mass ratio of PLGA to lithium chloride is 75:5. And PLGA (polylactic acid-glycolic acid copolymer) was purchased from Shandong Provincial Institute of Medical Devices, the molecular weight of PLGA was 100,000, and the molar ratio of lactic acid to glycolic acid was 50:50; TCP was purchased from Beijing Modern Oriental Fine Chemical Products Co., Ltd. Lithium chloride was purchased from Sigma with a purity greater than 99%; and the biomaterial rapid prototyping machine was developed by the Department of Mechanical Engineering, Tsinghua University, model CLRF-2000-II.

[0053] The preparation method of the biocomposite material comprises the following steps:

[0054] S21: Weigh 3.75g PLGA, place it in a 50ml small beaker, pour the solution containing TCP, and stir overnight at room