The invention discloses a structure design method of a strand compacted non-rotating steel wire rope with the diameter of 45mm. The method particularly includes the steps: firstly, taking a center fiber core as a center, externally wrapping the center fiber core with six twisted inner-layer strands, compacting the inner strands by a roller after the inner strands are twisted and formed, enabling the compaction rate of each strand to be 12-15%, and forming a first rope; secondly, taking the first rope as a center, externally wrapping the first rope with eleven twisted secondary outer strands, compacting the secondary outer strands by the roller after the secondary outer strands are twisted and formed, enabling the compaction rate of each strand to be 12-15%, and forming a second rope; thirdly, taking the second rope as a center, externally wrapping the second rope with seventeen twisted outer strands, compacting the outer strands by a roller after the outer strands are twisted and formed, and enabling the compaction rate of each strand to be 12-15%. According to the method, the inner strands, the secondary outer strands and the outer strands of the steel wire rope are compacted by the roller, surface contact of one steel wire and the other steel wire in the corresponding strand is achieved, partial linear contact between the strands is achieved, and the steel wire rope is compact in structure, good in fatigue resistance and rotation resistance, high in carrying capacity and long in service life.