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4 results about "Dextran" patented technology

Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose). IUPAC defines dextrans as "Branched poly-α-d-glucosides of microbial origin having glycosidic bonds predominantly C-1 → C-6". Dextran chains are of varying lengths (from 3 to 2000 kilodaltons).

Antigen-specific T lymphocyte freezing medium and preparation method and application thereof

ActiveCN107148967AReduce operating proceduresLow pollution rateDead animal preservationSodium Chloride InjectionT lymphocyte
The invention provides an antigen-specific T lymphocyte freezing medium, comprising freezing medium A and freezing medium B; the freezing medium A includes, by volume, 30-40% of plasmalyte electrolyte injection, 30-40% of glucose and sodium chloride injection, 5-15% of dextran glucose injection and 15-25% of human albumin solution; the freezing medium B includes, by volume, 20-30% of plasmalyte electrolyte injection, 20-30% of glucose and sodium chloride injection, 5-15% of dextran glucose injection, 15-25% of human albumin solution and 10-20% of dimethyl sulfoxide; the freezing medium A and the freezing medium B are stored separately; in use, the freezing medium A and the freezing medium B are mixed in a ratio of 1:(0.5-2), forming the antigen-specific T lymphocyte freezing medium. The antigen-specific T lymphocyte freezing medium is capable of enabling less crystal to form in cells, increasing cell survival rate and maintaining tumor-killing ability of cells. The invention also provides a preparation method and application of the antigen-specific T lymphocyte freezing medium and antigen-specific T lymphocyte injection.
Owner:CHENZHOU BINZE MEDICAL LAB CO LTD

Method for preparing hemostatic material based on air jet pulverization technology

The invention discloses a method for preparing a hemostatic material based on an air jet pulverization technology. The method comprises the following steps of (1) preparing a fibrinogen solution, wherein the fibrinogen solution comprises the following components of 2.5-3.5 wt% of fibrinogen, 10-25 wt% of trehalose, 2-10 wt% of glycine, 1.0-1.5 wt% of sodium chloride, 0.1-0.6 wt% of sodium citrate, 2.0-2.5 wt% of arginine hydrochloride and the balance of water for injection; (2) performing freeze drying on the fibrinogen solution, and performing air jet pulverization to obtain fibrinogen powder; (3) preparing a thrombin solution, wherein the thrombin solution is prepared from the following components of 0.1 to 0.5 weight percent of thrombin, 1.5 to 5.0 weight percent of trehalose, 0.3 to 1.0 weight percent of calcium chloride, 0.5 to 2.0 weight percent of glycine, 1.0 to 3.0 weight percent of cane sugar, 0.5 to 2.0 weight percent of dextran 20 and the balance of water for injection; (4) performing freeze drying on the thrombin solution, and performing air jet pulverization to obtain thrombin powder; and (5) mixing the fibrinogen powder with the thrombin powder, filling and drying to obtain the hemostatic material. The preparation process is simple, the period is short, and the prepared material is convenient to clinically use and excellent in hemostatic effect and has a wider application prospect.
Owner:FUDAN UNIV
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