Array chip mass spectrometry analysis method of photoelectrochemical reaction intermediate

[0028] Detection of intermediates in mitoxantrone photooxidation reaction using titanium dioxide-modified array chip coupled with electrostatic spray ionization mass spectrometry. Include the following steps:

[0029] Take 0.1g of Degussa P25 titanium dioxide, grind it in a mortar for 1 hour, add 1 ml of 1% acetic acid dropwise during the grinding process, disperse the ground titanium dioxide powder in 1 ml of ethanol, and dilute it 25 times in water to obtain 4 milligrams per milliliter of titanium dioxide suspension. The suspension was modified on the glass surface by inkjet printing technology to form an array chip. The chips were burned at 400°C for one hour and cooled naturally.

[0030] Add 0.4 millimoles per liter, 1 microliter of mitoxantrone aqueous solution dropwise on the surface of a glass sheet modified with titanium dioxide, and use electrostatic spray ionization mass spectrometry to directly detect it. The square wave pulse high voltage used in the detection is 0

[0033] Detection of intermediates in photooxidation of mitoxantrone using graphene-modified polyimide array chip coupled with electrostatic spray ionization mass spectrometry.

[0034] Graphene oxide ink formulation: 3 mg of graphene oxide flakes (Nanjing Pioneer Nanomaterial Technology Co., Ltd.) and 50 mg of polyvinylpyrrolidone (PVP) powder were added to 1 mL of water:isopropanol (3:1) mixture, and Sonicate by on / off cycle at 35% amplitude for 180 min in a 2 mL centrifuge tube. The final dispersion concentration was 3 mg / ml of graphene oxide. Then, the dispersion was centrifuged at 13000 g Centrifuge for 20 minutes and remove the supernatant. Thereafter, the precipitate was redispersed in 1 ml of a 1,2-propanediol-based mixture containing 10% terpineol.

[0035] Use an inkjet printer to print the above ink onto the surface of a polyimide substrate (0.2 mm thickness) to form an array of dots with a diameter of 0.2 mm, and use light curing to stabilize the printed layer.