Microbial hyperswarmers and uses thereof
a hyperswarmer and microorganism technology, applied in the field of microorganism hyperswarmers, can solve the problems of common gastrointestinal diseases in farm animals and fatal health problems, and achieve the effect of treating or preventing intestinal inflammation
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[0022]The invention provides a method of treating or preventing an intestinal inflammation in a subject comprising administering to the gastrointestinal tract of the subject bacterial hyperswarmers in an amount effective to treat or prevent an intestinal inflammation in a subject.
[0023]As used herein, bacterial “swarmers” refers to bacteria or strains of bacteria that aggregate and travel in the same direction. Bacterial “hyperswarmers” are identified by collective migration of bacteria over a surface that out competes its swarming counterpart and is growth independent in this activity. Hyperswarmers are out competed by counterpart swarming and non-swarming strains in biofilm formation. Hyperswarmers are intrinsically poor biofilm formers.
[0024]As used herein, “treating” or “treat” a condition means to alleviate or ameliorate or eliminate a sign or symptom of the condition that is being treated. The subject being treated can have, for example, one or more of inflammatory bowel disea...
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