4 results about "Blood concentration" patented technology

The invention relates to a blood disease related drug concentration detection method and application, and the method comprises the following steps: mixing a blood sample to be detected with a cell lysis solution or a buffer salt solution, adding a methanol solution of an isotope internal standard of the drug to be detected, oscillating, carrying out centrifugal separation, and collecting the supernatant; injecting the supernatant into a rapid liquid chromatography system for separation and analysis, then entering a triple quadrupole mass spectrometry detector, collecting and processing data through chromatographic software, and calculating the drug concentration in a blood sample to be detected. According to the blood disease related drug concentration detection method, according to the characteristics and clinical needs of the blood diseases, a scheme for detecting the blood concentration of the medicines related to the blood diseases is established, and the scheme has the advantagesthat a chromatographic column and a mobile phase do not need to be replaced, so that the detection efficiency and the operation convenience are greatly improved, and the method is suitable for large-scale clinical popularization.