Method for preparing adhesive solution in wet granulation process
A binder solution, wet granulation technology, applied in the field of pharmacy, can solve the problems of complex binder components, difficult realization of clear solution, poor water solubility, etc.
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Embodiment 1
[0036] It is weighted 450 g of purified water, and the purified water is stirred to form a vortex, weigh 25.4 g of the poloxham P407, and the stirred water is slowly added, stirred to form a uniform transparent solution. The purified water of 25 g was added, 0.7 g NaOH was added, stirred until dissolved. The aqueous sodium hydroxide solution was slowly added to a container containing a water solution of a water, and a beaker of the NaOH solution was dissolved with 25 g of water, and 17.4 g of glucamine was added, then 17.4 g of glucamine, continued to stir up and finally obtained a clear clear clarification. Solution (see figure 1 3 cups).
Embodiment 2
[0039] Example 2 Comparison of clarity
[0040] The solution obtained from the Solution 1, 2, 3 and Example 1 was placed in the absorbent tank of the spectrophotometer, and the absorbance was determined at 550 nm, and the results were shown in Table 1 and image 3 .
[0041] Table 1, 4 samples of ultraviolet visible light absorbance and relative turbidity at 550 nm
[0042]
[0043] The test results indicate that the solution obtained in Example 1 was crystal clear, and the difference was significant.
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