The invention discloses a ternary metal catalyst with excellent chlorine resistance and efficient catalytic oxidation of mixed VOCs, and belongs to the field of catalytic chemistry and nano science. The preparation method comprises the following steps: firstly, synthesizing ternary metal catalyst nanoparticles by adopting a solvothermal method, then loading the obtained nanoparticles on a TiO2 carrier by adopting an adsorption method, and finally centrifuging, drying and roasting to obtain the PtWM/TiO2 (M = Ru, Cr and Mn) catalyst, thereby finally achieving the excellent chlorine resistance to chlorine-containing VOCs, namely trichloroethylene (TCE) and the efficient catalyst for co-catalytic oxidation of toluene and TCE. The preparation process is simple, and the obtained PtWM/TiO2 (M = Ru, Cr or Mn) catalyst has high acidity, good chlorine resistance and excellent catalytic activity for co-catalytic oxidation reaction of toluene and trichloroethylene.