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9 results about "Alkaloid" patented technology

Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.

Recomposed escherichia coli base cell for efficient synthesis of terpene chemical compounds as well as preparation method and application thereof

ActiveCN103773729AAbundant resourcesGood synthesis effectBacteriaMicroorganism based processesEscherichia coliLycopene
The invention relates to a recomposed escherichia coli base cell for efficient synthesis of terpene chemical compounds as well as a preparation method and application thereof. Particularly, an escherichia coli endogenous 2-C-methyl-D-erythritol-4-phosphoric acid (MEP) precursor pathway is reconstructed; the reconstructed escherichia coli base cell is utilized to perform the efficient biological synthesis of the terpene chemical compounds; the reconstruction of the precursor pathway mainly comprises the steps of fully digging the MEP precursor pathway gene modules of the sources of other natural microorganisms, screening gene modules with excellent characteristics to be expressed in the escherichia coli, and at the same time, performing the downstream synthesis pathway for integrally assembling the colibacillus chemical compounds in the reconstructed base cell, wherein the colibacillus chemical compounds include sesquiterpene chemical compounds such as amorphadiene, diterpene chemical compounds such as shell alkene, tetraterpenes chemical compounds such as lycopene, polyterpene chemical compounds, other terpene alkaloid chemical compounds and the like. The escherichia coli base cell can remarkably facilitate the synthesis of the terpene chemical compounds.
Owner:CAS CENT FOR EXCELLENCE IN MOLECULAR PLANT SCI

Method for preparing test solution for quality detection of safe stagnation removing preparation

InactiveCN102539588AEliminate distractionsGood for qualitative and quantitative analysisComponent separationSolventAlkaloid
The invention relates to a method for preparing a test solution for quality detection of a safe stagnation removing preparation. The method comprises the following steps of: (1), extracting solution preparation: weighting 0.5-10.0g of solid safe stagnation removing preparation or contents thereof, adding a universal solvent for extracting alkaloid, carrying out ultrasonic treatment or heating backflow, cooling down, and filtering to obtain a filter liquid as an extract liquid for later use; or weighting 4-80ml of liquid safe stagnation removing preparation, and filtering to obtain the filter liquid as the extract liquid for later use; and (2) extract liquid purification: taking out the extract liquid, drying through steaming, dissolving residues by adding 1-10ml of hydrochloric acid solution (1-5,000) to the residues, centrifuging a mixed solution, taking out supernatant to slowly pass through an octadecylsilane bonded silica gel column (50-500mg), eluting by water of 2-30ml, collecting an effluent liquid and an eluting liquid, drying by steaming, dissolving the residues by adding 1-10ml of methanol with the volume percent of 30-100% or alcohol with the volume percent of 50-95%, standing, and taking out supernatant which is the test solution for a leonurus indexity element stachydrine hydrochloride thin layer discriminating and/or content determining method in the safe stagnation removing preparation.
Owner:YUNNAN LIANGFANG PHARMA

Preparation method of traditional Chinese medicine composition for purifying mandarin fish ponds

ActiveCN105394109AGood antivirus effectEfficient in situ bioremediationBiocideDisinfectantsMicrocrystalline waxBaical Skullcap Root
The invention discloses a preparation method of traditional Chinese medicine composition for purifying mandarin fish ponds. The method comprises steps as follows: baical skullcap roots, black nightshade herbs, fresh ginger, pomegranate rinds, red peony roots, cyrtomium rhizomes, perilla stems, peonies, arnebia roots, liquorice roots, argy wormwood leaves, stemona roots, acanthopanax root bark, tobacco leaves, pepper and ageratum are crushed, screened through a sieve of 60-70 meshes, soaked in water, heated and cooked until the moisture content is 20wt%-45wt%, hydroxyethyl cellulose is added, the mixture is stirred and granulated, and first preformed materials are obtained; alkaloid, Celastrus angulatus, Artemisia toosendanin, orange terpenes, pyrethrins and poly(aspartic acid) are evenly stirred, stir-fried shells, illite, illite smectite clay, diethylene glycol butyl acetate and microcrystalline wax are added and stirred, the mixture is atomized and sprayed onto surfaces of the first preformed materials, and second preformed materials are obtained; Celastrus angulatus missible oil, sodium carboxymethylcellulose, nacre mothers of pearls, activated carbon, an EM (effective microorganisms) liquid and water are evenly mixed, the mixture is atomized and sprayed onto surfaces of the second preformed materials, the second preformed materials are dried and screened, and the traditional Chinese medicine composition for purifying the mandarin fish ponds is obtained.
Owner:全椒县鮰鱼养殖专业合作社

HPLC with evaporative Light-scatter measuring method for huangyangning, cyclovirobuxine D, buxus alkaloid and relative alkaloid content

InactiveCN101042378AModerate sensitivityStrong specificityComponent separationBuxusEvaporation
This invention discloses one high effective liquid phase spectrum evaporation diffusion test method for Huangyangning, ring Huangyangxing D and Huangyangsheng alkaloid and relative contents, which comprises the following steps: its color spectrum is fixed with silicon gel as stuff agent; the flow phase adopts tetrahydrofuran - carbinol - acetonitrile - intense ammonial solution or acetic acid ethyl ester - carbinol - intense ammonial solution; the test device adopts evaporation diffusion light tester.
Owner:杭太俊 +5

Purpose of herba leonuri extract total alkaloids for treating prostatic hyperplasia and prostatitis

InactiveCN101040902AOpen up new usesUrinary disorderPlant ingredientsMotherwortProstate hyperplasia
The invention relates to alkaloids extracted from motherwort and the use in treating prostate hyperplasia and prostatitis, wherein the motherwort alkaloids is prepared from motherwort through grilling twice with water, filtering, merging the filter liquor and thickening, charging ethanol, adjusting acidity with hydrochloric acid, stewing till the second day, filtering, drying the filtrate to obtain dry matter.
Owner:苗明三

Tibetan medicine composition with effect of treating rheumatoid arthritis as well as preparation method and application of Tibetan medicine composition

ActiveCN114848703ACompound composition is simpleGood treatment effectAntipyreticAnalgesicsPharmacometricsPharmaceutical drug
The invention belongs to the field of medicines, and particularly relates to a Tibetan medicine formula with an effect of treating rheumatoid arthritis, a preparation method and application. The Tibetan medicine formula with the effect of treating rheumatoid arthritis is characterized by being prepared by mixing and crushing 9-15 parts of Tibetan cat milk, 3-10 parts of gentiana macrophylla, 3-10 parts of cortex berberidis and 3-10 parts of fructus chebulae, adding water, performing reflux extraction and drying. According to the compound medicine provided by the invention, the rationality and effectiveness of the compound composition are confirmed by combining the research results of related pharmacology experiments and the results of animal experiments. The compound provided by the invention is a combination of four medicines according to a specific ratio, and a specific extraction process is combined, so that the contents of active ingredients such as flavones and alkaloids in the final compound are ensured, the treatment effect of the compound on RA is obviously superior to that of each single medicine in the compound, and the compound has a remarkable synergistic interaction effect.
Owner:QINGDAO UNIV OF SCI & TECH +1

Alkaloid compound, preparation method and application

The invention belongs to a natural extraction compound as well as a preparation method and application thereof. In order to solve the technical problems that existing hypoglycemic drugs are more in variety, the side effect is still great, the curative effect on complications is poor and the drug resistance easily occurs with medication time extension, the invention provides an alkaloid compound aswell as a preparation method and application thereof. The molecular formula of the alkaloid compound is C46H63N3O23, and the compound is an indoline dimer alkaloid. The preparation method comprises the following steps: extracting total extract from calanthe discolor, extracting the total extract, and carrying out column chromatography separation on an n-butyl alcohol extraction layer. The preparation method is simple, convenient and effective, the alkaloid compound is obtained, the purity is high, the cost is low, and verification proves that the alkaloid compound can be applied to anti-inflammatory drugs and anti-diabetic drugs.
Owner:XI AN JIAOTONG UNIV
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