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3 results about "Hapten" patented technology

Q: How to Hapten?

Enzyme-linked immunologic detection method of bisphenol A,Preparation method of stress phosphorylation antibody aiming at human Tudor-SN protein T103 site,Test strip for detecting organophosphorus pesticide and application thereof

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Haptens are relatively small molecules that elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one that also does not elicit an immune response by itself (in general, only large molecules, infectious agents, or insoluble foreign matter can elicit an immune response in the body). Once the body has generated antibodies to a hapten-carrier adduct, the small-molecule hapten may also be able to bind to the antibody, but it will usually not initiate an immune response; usually only the hapten-carrier adduct can do this. Sometimes the small-molecule hapten can even block immune response to the hapten-carrier adduct by preventing the adduct from binding to the antibody, a process called hapten inhibition.

Enzyme-linked immunologic detection method of bisphenol A

InactiveCN101413945AHigh selectivityIncreased sensitivityMaterial analysis by observing effect on chemical indicatorElisa methodImmuno detection

An enzyme-linked immunoassay method of bisphenol A belongs to the technical field of immunodetection. The enzyme-linked immunosorbent assay method utilizes the immunization of a synthetic bisphenol A immunogen to obtain a polyclonal antibody, takes the bisphenol A as a standard product, takes a conjugate of a hapten of diphenolic acid and OVA as a coating antigen and establishes the indirect competitive enzyme-linked immunosorbent assay method of the bisphenol A. The enzyme-linked immunosorbent assay method establishes the indirect competitive ELISA method of the bisphenol A and provides a rapid and high-efficient detection method for detecting the residual bisphenol A, as the method adopts the polyclonal antibody, the cost is lower, and the stability and the repeatability are good. The sensitivity is 0.1ng / ml, and the linear range is 0-100ng / ml. The high specificity and the affinity of the immune reaction lead the ELISA to have very high selectivity and sensitivity.

Owner:JIANGNAN UNIV