The invention discloses a method for synthesizing 3-(methylthio) dibenzenamine by light /
nickel concerted
catalysis. According to the method, cheap 3-(methylthio) benzenamine and halogeno
benzene are used as raw materials, a light /
nickel concerted
catalysis strategy is used for constructing C-N bonds for the first time, and pyridazines
drug key intermediate 3-(methylthio) dibenzenamine is synthesized. The method has the advantages that 1) the use amount of a photocatalyst is low, and is 0.01-0.02% of the
molar weight of the halogeno
benzene; 2)
nickel salt is directly used as a
metal catalyst such as nickel
bromide, and an external ligand is not required; 3)
reaction conditions are gentle, and can be effectively carried out at the temperature of 40-50 DEG C; and 4) the product can be directly obtained by reduced pressure
distillation and is easily separated. By the remarkable advantages, the method has good industrial application prospect.