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2 results about "Antimicrobial peptides" patented technology

Antimicrobial peptides (AMPs), also called host defense peptides (HDPs) are part of the innate immune response found among all classes of life. Fundamental differences exist between prokaryotic and eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes, can form transmembrane channels, and may also have the ability to enhance immunity by functioning as immunomodulators.

Analogous CecroPinP1 antimicrobial peptide and application thereof

InactiveCN107746431AGrowth inhibitionPromote growthAntibacterial agentsPeptide/protein ingredientsBacteroidesEscherichia coli
The invention discloses a CecroPinP1-like antibacterial peptide and its application, belonging to the technical field of biochemistry and molecular biology. The CecroPinP1-like antimicrobial peptide consists of 21 amino acids, and its amino acid sequence is shown in SEQ ID NO:1. CecroPinP1-like antibacterial peptides can inhibit Escherichia coli, Streptococcus pneumoniae, Salmonella typhimurium, Clostridium perfringens type C, Staphylococcus aureus, Listeria monocytogenes, Pasteurella and other bacteria Compared with doxycycline hydrochloride, amoxicillin, colistin sulfate and other antibiotics, the antibacterial effect is relatively better, and compared with CecroPinP1 antimicrobial peptide, it has stronger antibacterial activity. The minimum inhibitory concentration (MIC) of the CecroPinP1-like antimicrobial peptide against Streptococcus pneumoniae reached 62.5 μg / mL. CecroPinP1-like antimicrobial peptides have good thermal stability, can promote the growth of livestock and poultry, and have good application prospects in the development of antibacterial drugs and animal husbandry.
Owner:GUANGZHOU JUNYA TECH APPL CO LTD
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