The invention discloses a non-resistant low-zinc low-copper non-plasma high-grade piglet creep feed and a preparation method thereof. The creep feed comprises the following raw materials: corn, flour,broken rice, puffed soybean powder, milk powder, imported fish meal or fish peptide protein, fermented soybean meal, yeast hydrolysate, soybean protein concentrate, fat powder, acidifying agent, fishsolubles, egg powder, calcium lactate, calcium dihydrogen phosphate, lysine, methionine, threonine, tryptophan, trace element composite package, coated zinc oxide, vitamin composite package, plant extract composite package, plant essential oil, antibacterial peptide and microecological preparation. The product does not use homologous proteins such as plasma protein powder so as to effectively block the occurrence of homologous diseases. The product uses low zinc and low copper so as to reduce environmental pollution and improve the utilization rate of land. The product is free from antibioticso as to reduce drug residue and to ensure human food health. The preparation method provided by the invention is simple, the raw material sources are wide, and the use effect is good.