12 results about "Quinoline" patented technology

The invention discloses a feed mould inhibitor, which is prepared by mixing sodium diacetate, ethoxy quinoline, eugenol, propionic acid, benzoic acid and vermiculite powder. The feed mould inhibitor has the advantages of rational formula, good mildew prevention effect, high efficiency, long effective period, safety, reliability, and low production cost.

The invention discloses a room-temperature preparation method of a metal-organic framework material preferentially adsorbing ethane. The preparation method comprises the following steps: dispersing zinc oxide and copper tetrafluoroborate hexahydrate in water and ethanol; dispersing quinoline-5-carboxylic acid in N,N-dimethylformamide; mixing the former solutions, and stirring an obtained mixed solution at room temperature; filtering the stirred solution to obtain a solid product, purifying, drying and performing vacuum activation to obtain the metal-organic framework material preferentially adsorbing the ethane. By the room-temperature preparation method, the metal-organic framework material with good alkane selectivity is prepared at room temperature, the synthesizing energy consumption of the material is reduced, and the prepared material has good adsorptive separation performance for ethylene-ethane gas at normal temperature and pressure. The material can preferentially adsorb the ethane from the ethylene-ethane mixed gas; in addition, the material has good water vapor stability, and still has a good crystal structure after 40-day direct exposure to air.

A 7-[4-[4-(2,3-dichlorophenyl)-1-piperazine]-2- butenoxy]-3,4-dihydro-2-(1H)-quinoline-2-one and its receptable salt, its preparing process featuring use of high-activity, 1,4-dibromo-2-butene to replace 1,4-bibromobutane, its application in preparing aripiperazole and the process for preparing aripiperazole are disclosed.

The invention discloses a method for synthesizing C-5-bit trifluoromethylated 8-aminoquinoline by using a micro-channel reaction device under visible light. The method comprises the following steps: dissolving a 8-aminoquinoline compound in a solvent to obtain a homogeneous solution A, and dissolving eosin Y and NaCF3SO2 in water to obtain a homogeneous solution B; and simultaneously pumping the prepared homogeneous solution A and homogeneous solution B into a micro-mixer of a micro-channel reaction device respectively, mixing, introducing into a micro-channel reactor of the micro-channel reaction device under irradiation of visible light, making reaction, and washing separating, extracting, concentrating, and recrystallizinga reaction effluent, to obtain the product. According to the method, the product of C-5-bit trifluoromethylated 8-aminoquinoline is prepared by using a micro-channel reaction device under visible light irradiation, compared with common reaction, the reaction time is shortened, the reaction conversion rate is increased, and the product yield reaches 79%-93%; the product is stable and additive-free and is beneficial to large-scale production; meanwhile, operationis easy, the safety is high, and the defects of a traditional reaction kettle can be effectively overcome.

The invention relates to a bactericidal composition containing pydiflumetofen and oxine-copper. The compound preparation is mainly prepared from pydiflumetofen and oxine-copper, and can be prepared into water dispersible granules and suspending agent spray. Indoor bacteriostasis and field test determination show that the compound preparation has a very good prevention and treatment effect on applealternaria leaf spot disease bacteria. The dosage form is environment-friendly in processing, high in selectivity and simple to use, and has extremely high operability and practical application value.

N-alkyl group-3, 6-di-(2-quinoline) vinyl) carbazole and a preparation method thereof relate to carbazole derivatives and preparation methods thereof and aim to solve the problems of poor thermal stability and photochemical stability of existing two-photon absorption materials. The structural formula of the N-alkyl group-3, 6-di-(2-quinoline) vinyl) carbazole is shown as follow, wherein the R is CnH2n+1 or benzyl, and the n ranges from 1 to 8. The preparation method of the N-alkyl group-3, 6-di-(2-quinoline) vinyl) carbazole includes: firstly, mixing 3, 6-dimethyl acyl-N-alkyl-carbazole, 2-methyl quinoline and acetic anhydride uniformly, then mixing with water uniformly and regulating the pH (potential of hydrogen) value to be 7.0; and secondly, extracting by dichloromethane, collecting extract and obtaining the N-alkyl group-3, 6-di-(2-quinoline) vinyl) carbazole. The carbazole derivatives of the N-alkyl group-3, 6-di-(2-quinoline) vinyl) carbazole have two-photon absorption function and fine dissolubility, thermal stability and photochemical stability. The N-alkyl group-3, 6-di-(2-quinoline) vinyl) carbazole can be applied to the technical field of two-photon absorption materials.

The invention belongs to the technical field of medicines, and discloses preparation and application of a medium-ring-containing tetrahydrocarboline-tetrahydroisoquinoline compound. The invention specifically relates to a compound shown in a general formula I and pharmaceutically acceptable salts thereof, a preparation method of the compound, a pharmaceutical composition containing the compound shown in the general formula I, a preparation method of the pharmaceutical composition and application of the compound and the pharmaceutical composition in the anti-tumor aspect.

The invention relates to substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol compounds, their synthesis, pharmaceutical compositions containing them, and methods of using them in the treatment of disorders benefiting from inhibition of vesicular monoamine transporter 2 (VMAT2).

The invention discloses a synthesis method of 6-(trifluoromethyl)quinoline-8-carboxylic acid. The method comprises the following steps of: condensing 2-bromo-4-(trifluoromethyl)aniline serving as a raw material with glycerol to obtain 8-bromo-6-(trifluoromethyl)quinoline, and acquiring 6-(trifluoromethyl)quinoline-8-carboxylic acid methyl ester under the condition of carbon monoxide pressurization, and finally, performing hydrolyzing in a lithium hydroxide aqueous solution to obtain the 6-(trifluoromethyl)quinoline-8-carboxylic acid. The synthesis method is simple in synthetic route, reasonable in process selection, low in raw material cost, simple and easily available in raw materials, convenient to operate and post-treat, high in total yield and easy to amplify, and can be used for large-scale production.