12 results about "Chemical structure" patented technology

The invention belongs to the field of analytical chemistry and particularly relates to a detecting method for determining various neurotransmitters on the basis of in situ derivation. The method is characterized in that 4'-carbonyl chloride-rhodamine is used as the derivative reagent for the first time, the ultrasonic assistance-in situ derivation-dispersive liquid-liquid microextraction technology is used to derive amino acid and monoamine neurotransmitters, and the ultra-high performance liquid chromatography triple quadrupoles tandem mass spectrum with multiple reaction monitoring modes is used to perform qualitative and quantitative detection; three internal standard substances (isoprenaline, 5-ketoindole-2-carboxylic acid and norleucine) are used for building the linear equations of the neurotransmitters of three chemical structures; the existence of the neurotransmitters is accurately determined by quantification through an internal standard method. The detecting method is simple, fast, high in sensitivity, good in selectivity, good in recovery rate, capable of fast and accurately determining the neurotransmitters, and the like.

The invention discloses a lip-care composition and a preparation method thereof. The lip-care composition comprises effective components including, by weight, 50-80 parts of C10-30 acid cholesterol/lanosterol mixed ester, 1-40 parts of vegetable oil and 5-25 parts of wax. The preparation method of the lip-care composition includes steps: mixing, to be specific, heating and dissolving wax, adding vegetable oil, mixing, heating to 75-90DEG C, and keeping the temperature for at least 30min to obtain a premix; mixed ester adding, namely adding the C10-30 acid cholesterol/lanosterol mixed ester into the premix, and mixing to obtain the lip-care composition. Due to high content of the C10-30 acid cholesterol/lanosterol mixed ester, the chemical structure of the lip-care composition is similar tothat of skin sebum, high hydrophilicity is realized, a stratum corneum not sticky to human skin is formed on the skin, regulation of skin moisture content and skin barrier function can be realized, and a high value in dry skin care is achieved.

The invention provides a lysosome fluorescent probe, a preparation method thereof and application of the lysosome fluorescent probe in observation of lysosome viscosity. The chemical structural formula of the fluorescent probe is shown in the specification. The fluorescent probe has the advantages of simple preparation method, low toxicity, simplicity in use and capability of finely observing viscosity change of lysosome.

The invention discloses a novel moisture-curing flame-retardant polyurethane hot melt adhesive and a preparation method thereof. The novel moisture-curing flame-retardant polyurethane hot melt adhesive is characterized by being prepared from 1-20 parts of polyether diols, 1-35 parts of liquid polyester diols, 1-40 parts of flame-retardant polyether glycol, 1-35 parts of crystalline polyester diols, 1-35 parts of an isocyanate-containing modified polyacrylic acid fluorosilicone copolymer, 1-50 parts of isocyanate, 0.01-1 part of a catalyst, 0.01-1 part of an antioxidant and 0.1-2 parts of a silane coupling agent. The isocyanate-containing modified polyacrylic acid fluorosilicone copolymer is synthesized firstly, the chemical structure of the copolymer is poly(hexafluorobutyl acrylate-random-monomethacryloxypropyl terminated polydimethylsiloxanes-random-methyl acrylate-random-isocyanatoethyl methacrylate, the copolymer is added to a polyurethane prepolymer and subjected to condensation polymerization, a fluorosilicone-containing acrylate copolymer chain segment and a reaction type flame retardant are introduced and have an efficient synergistic effect, and therefore, comprehensive chemical resistance, oil resistance, water resistance and flame retardance are improved.

The invention discloses bis-fluoroquinolone thiadiazole urea N-methyl enoxacin derivatives as well as a preparation method and an application thereof. The general chemical structure formula of the derivatives is shown in the formula I as follows in the description. In the formula I, R is ethyl, cyclopropyl, fluoroethyl, an oxazine ring consisting of C-8 or a thiazine ring consisting of C-8; L is an independent Cl or F atom, 1-piperazinyl or substituted piperazine-1-yl or a nitrogen fused heterocyclic ring; X is CH, N or F-substituted C atom (F-C) or a methoxy substituted C atom (CH3O-C). The bis-fluoroquinolone thiadiazole urea N-methyl enoxacin derivatives realize organic combination of a bis-fluoroquinolone skeleton and the thiadiazole heterocyclic ring with functional urea pharmacophores, so that transition and superposition of different pharmacophores are realized, anti-tumor activity and selectivity of fluoroquinolone are increased, toxic and side effects on normal cells are reduced, and the derivatives can be taken as an anti-tumor active substance for developing anti-tumor drugs with novel structures.

A method for improving the ferrous corrosion-preventing characteristics of a fuel comprises combining an additive having a chemical structure comprising a 6-membered aromatic ring sharing two adjacent aromatic carbon atoms with a 6- or 7-membered saturated heterocyclic ring, the 6- or 7-membered saturated heterocyclic ring comprising a nitrogen atom directly bonded to one of the shared carbon atoms to form a secondary amine and an atom selected from oxygen or nitrogen directly bonded to the other shared carbon atom, the remaining atoms in the 6- or 7-membered heterocyclic ring being carbon with the fuel. The additive may also be used for preventing ferrous corrosion in a system which comprises a fuel, such as a fuel system in a vehicle.