Application of protein nano-selenium in preparation of medicine for preventing and treating oral diseases

[0013] The preparation of embodiment 1 albumin nano selenium

[0014] According to the preparation method described in Example 1 of the Chinese patent application whose application number is 201810166924.7, the protein-bound nano-selenium element prepared is the albumin nano-selenium of this embodiment, and the obtained albumin nano-selenium particles have a uniform nanometer size. The distribution is uniform, and the average particle size is about 30-40nm.

[0015] The preparation of embodiment 2 nano-selenium mouthwash

[0016] Take 10mL of edible vinegar and 400mL of ultrapure water, mix them evenly, then add 10mL of nano-selenium, and mix well to get the nano-selenium mouthwash that can be used. Because it is easy to aggregate, it needs to be shaken before use to get the nano-selenium mouthwash. At the same time, 10 mL of nano-selenium was added to 400 mL of normal saline to prepare the nano-selenium group for the experiment.

[0017] The preparation of embodiment 3 albumin nano-selenium mouthwash

[0018] Take 10 mL of edible vinegar and 400 mL of ultrapure water, mix them evenly, then add 10 mL of albumin nano-selenium obtained in Example 1, and mix well to obtain a usable albumin nano-selenium mouthwash.